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1. (WO2012106356) VIRUS-LIKE PARTICLES AND METHODS OF USE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/106356    International Application No.:    PCT/US2012/023361
Publication Date: 09.08.2012 International Filing Date: 31.01.2012
IPC:
A61K 39/12 (2006.01), C12N 7/00 (2006.01)
Applicants: THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES [US/US]; Office of Technology Transfer, National Institutes of Health 6011 Executive Boulevard, Suite 325 MSC 7660 Bethesda, MD 20892-7660 (US) (For All Designated States Except US).
NABEL, Gary, J. [US/US]; (US) (For US Only).
RAO, Srinivas [US/US]; (US) (For US Only).
AKAHATA, Wataru [JP/US]; (US) (For US Only)
Inventors: NABEL, Gary, J.; (US).
RAO, Srinivas; (US).
AKAHATA, Wataru; (US)
Agent: CONNELL, Gary, J.; Sheridan Ross P.C. 1560 Broadway, Suite 1200 Denver, CO 80202 (US)
Priority Data:
61/438,236 31.01.2011 US
61/501,012 24.06.2011 US
Title (EN) VIRUS-LIKE PARTICLES AND METHODS OF USE
(FR) PARTICULES PSEUDO-VIRALES ET PROCÉDÉS D'UTILISATION
Abstract: front page image
(EN)The invention features modified alphavirus or flavivirus virus-like particles (VLPs). The invention provides methods, compositions, and kits featuring the modified VLPs. The invention also features methods for enhancing production of modified VLPs for use in the prevention or treatment of alphavirus and flavivirus-mediated diseases. The invention also provides methods for delivering agents to a cell using the modified VLPs.
(FR)L'invention concerne des particules pseudo-virales (VLP) alpha-virales ou flavivirales modifiées. L'invention concerne des procédés, des compositions et des kits comprenant les VLP modifiées. L'invention concerne également des procédés pour améliorer la production de VLP modifiées destinées à être utilisées dans la prévention ou le traitement de maladies médiées par les alphavirus et les flavivirus. L'invention concerne également des procédés d'administration d'agents à une cellule au moyen des VLP modifiées.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)