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Pub. No.:    WO/2012/104869    International Application No.:    PCT/IN2012/000069
Publication Date: 09.08.2012 International Filing Date: 30.01.2012
A61P 3/00 (2006.01), A61K 31/40 (2006.01)
Applicants: CADILA HEALTHCARE LIMITED [IN/IN]; Zydus Tower, Satellite Cross Roads Ahmedabad 380015 Gujarat (IN) (For All Designated States Except US).
GAMBHIRE, Dhiraj [IN/IN]; (IN) (For US Only).
JANI, Rajendrakumar Hariprasad [IN/IN]; (IN) (For US Only).
PANDEY, Bipin [IN/IN]; (IN) (For US Only).
SATA, Kaushik [IN/IN]; (IN) (For US Only).
KOTHARI, Himanshu [IN/IN]; (IN) (For US Only).
PATEL, Pankaj Ramanbhai [IN/IN]; (IN) (For US Only)
Inventors: GAMBHIRE, Dhiraj; (IN).
JANI, Rajendrakumar Hariprasad; (IN).
PANDEY, Bipin; (IN).
SATA, Kaushik; (IN).
KOTHARI, Himanshu; (IN).
PATEL, Pankaj Ramanbhai; (IN)
Agent: SUBRAMANIAM, Hariharan; Subramaniam, Nataraj & Associates E- 556, Greater Kailash-II New Delhi 110048 (IN)
Priority Data:
257/MUM/2011 31.01.2011 IN
Abstract: front page image
(EN)The present invention provides a therapeutic compound of formula (I) and their pharmaceutically acceptable salts for the prevention and treatment of lipodystrophy caused because of HIV infection or combination therapy of HIV-1 protease inhibitors (Pis) and/or reverse transcriptase inhibitors (nRTIs) by neutralizing lipohypertrophy, lipoatrophy and metabolic abnormalities in HIV patient.
(FR)La présente invention concerne un composé thérapeutique de formule (I) et ses sels pharmaceutiquement acceptables pour la prévention et le traitement de la lipodystrophie causée par une infection par le VIH ou une plurithérapie à base d'inhibiteurs de la protéase du VIH-1 (PI) et/ou d'inhibiteurs de la transcriptase inverse (nRTI) par neutralisation de la lipohypertrophie, de la lipoatrophie et des anomalies métaboliques chez un patient infecté par le VIH.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)