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Machine translation
1. (WO2012104824) THERAPEUTIC ANTIBODIES TARGETING APP-C99
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/104824    International Application No.:    PCT/IB2012/050515
Publication Date: 09.08.2012 International Filing Date: 03.02.2012
IPC:
C07K 16/18 (2006.01)
Applicants: ECOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE (EPFL) [CH/CH]; EPFL-TTO Quartier de l'innovation - J CH-1015 Lausanne (CH) (For All Designated States Except US).
FRAERING, Patrick [FR/CH]; (CH) (For US Only).
HOUACINE, Jemila [FR/CH]; (CH) (For US Only).
BOLMONT, Tristan [FR/CH]; (CH) (For US Only).
AESCHBACH, Lorène [CH/CH]; (CH) (For US Only).
OULAD-ABDELGHANI, Mustapha [FR/FR]; (FR) (For US Only)
Inventors: FRAERING, Patrick; (CH).
HOUACINE, Jemila; (CH).
BOLMONT, Tristan; (CH).
AESCHBACH, Lorène; (CH).
OULAD-ABDELGHANI, Mustapha; (FR)
Agent: KATZAROV S.A.; Rue des Epinettes 19 CH-1227 Geneva (CH)
Priority Data:
0209/11 04.02.2011 CH
Title (EN) THERAPEUTIC ANTIBODIES TARGETING APP-C99
(FR) ANTICORPS THÉRAPEUTIQUES CIBLANT APP-C99
Abstract: front page image
(EN)The present invention relates to an isolated and/or purified antibody, antibody fragment or derivative thereof able to block the gamma-secretase-dependent processing of the amyloid precursor protein (APP) and to pharmaceutical compositions containing said antibody/ies.
(FR)La présente invention concerne un anticorps isolé et/ou purifié, un fragment d'anticorps ou un dérivé de celui-ci pour bloquer le traitement gamma-sécrétase-dépendant de la protéine précurseur d'amyloïde (APP) et des compositions pharmaceutiques contenant ledit/lesdits anticorps.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)