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1. (WO2012104788) ANTI-ANGIOGENIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND USE THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/104788    International Application No.:    PCT/IB2012/050452
Publication Date: 09.08.2012 International Filing Date: 31.01.2012
IPC:
A61K 31/495 (2006.01), A61K 31/18 (2006.01), A61K 31/473 (2006.01), A61P 35/00 (2006.01), C07D 221/14 (2006.01), C07D 295/192 (2006.01), C07D 295/13 (2006.01)
Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE [--/FR]; 3, rue Michel Ange F-75016 Paris (FR) (For All Designated States Except US).
FEIGE, Jean-Jacques [FR/FR]; (FR) (For US Only).
CASTAN, Agnès [FR/FR]; (FR) (For US Only).
QUELARD, Delphine [FR/FR]; (FR) (For US Only).
DEMEUNYNCK, Martine [FR/FR]; (FR) (For US Only).
CONSTANT, Jean-François [FR/FR]; (FR) (For US Only).
BARETTE, Caroline [FR/FR]; (FR) (For US Only)
Inventors: FEIGE, Jean-Jacques; (FR).
CASTAN, Agnès; (FR).
QUELARD, Delphine; (FR).
DEMEUNYNCK, Martine; (FR).
CONSTANT, Jean-François; (FR).
BARETTE, Caroline; (FR)
Agent: DIAS, Sonia; Cabinet Ores 36 rue de Saint Petersbourg F-75008 Paris (FR)
Priority Data:
11 00277 31.01.2011 FR
Title (EN) ANTI-ANGIOGENIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND USE THEREOF
(FR) COMPOSES ANTI-ANGIOGENIQUES, COMPOSITIONS PHARMACEUTIQUES LES COMPRENANT, ET LEUR UTILISATION
Abstract: front page image
(EN)The invention relates to compounds of formula (A) having an anti-angiogenic and/or anti-tumoral activity, to pharmaceutical compositions comprising same, and to the use thereof for treating cancer. (substituted) N-(CH2)m-A-Rc where A is a bond, Het-(CH2)1-6 or NH-(CH2)1-6 and Rc is O-substituted or N-substituted.
(FR)La présente invention concerne des composés de formule (A) ayant une activité anti-angiogénique et/ou antitumorale, les compositions pharmaceutiques les comprenant et leur utilisation dans le traitement du cancer. (substitué) N-(CH2)m-A-Rc Oú A est une liaison, Het-(CH2)1-6 ou NH-(CH2)1-6 et Rc est O-substitué ou N-substitué
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: French (FR)
Filing Language: French (FR)