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Machine translation
1. (WO2012104589) WEIGHT RELATED DISORDERS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/104589    International Application No.:    PCT/GB2012/000108
Publication Date: 09.08.2012 International Filing Date: 02.02.2012
IPC:
A61K 31/105 (2006.01), A61K 31/185 (2006.01), A61K 31/4402 (2006.01), A61K 31/4406 (2006.01), A61K 31/4409 (2006.01), A61K 31/505 (2006.01), C12N 15/85 (2006.01), A61P 3/10 (2006.01)
Applicants: UNIVERSITY OF EDINBURGH [GB/GB]; Old College South Bridge Edinburgh EH8 9YL (GB) (For All Designated States Except US).
MORTON, Nicholas M. [GB/GB]; (GB) (For US Only).
WEBSTER, Scott [GB/GB]; (GB) (For US Only)
Inventors: MORTON, Nicholas M.; (GB).
WEBSTER, Scott; (GB)
Agent: GIBBS, Richard; Marks & Clerk LLP Aurora 120 Bothwell Street Glasgow G2 7JS (GB)
Priority Data:
1101793.6 02.02.2011 GB
Title (EN) WEIGHT RELATED DISORDERS
(FR) TROUBLES LIÉS AU POIDS
Abstract: front page image
(EN)The present invention concerns the finding that expression of the gene encoding the enzyme, thiosulfate sulphur transferase and the activity or function of the TsT enzyme itself, is elevated in the tissues of lean animals. Consequently, the invention provides compositions, methods and medicaments for treating or preventing weight related disorders as well as methods and assays for diagnosing or detecting a weight related disorder and/or a predisposition/susceptibility thereto.
(FR)La présente invention concerne la découverte selon laquelle l'expression du gène codant pour l'enzyme, thiosulfate sulfurtransférase et l'activité ou fonction de l'enzyme TsT elle-même, sont élevées dans les tissus d'animaux maigres. Par conséquent, l'invention concerne des compositions, méthodes et médicaments pour traiter ou prévenir des troubles liés au poids ainsi que des méthodes et des dosages pour le diagnostic ou la détection d'un trouble lié au poids et/ou une prédisposition/vulnérabilité à un tel trouble.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)