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Machine translation
1. (WO2012104500) NOVEL PEPTIDES INVOLVED IN THE SCF C-KIT SIGNALLING PATHWAY AND COMPOSITIONS COMPRISING SAME
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/104500    International Application No.:    PCT/FR2012/000035
Publication Date: 09.08.2012 International Filing Date: 30.01.2012
IPC:
C07K 5/10 (2006.01), C07K 7/06 (2006.01), C07K 7/08 (2006.01), A61K 8/64 (2006.01)
Applicants: ISP INVESTMENTS INC. [US/SA]; 1101 Centre Road, Suite 315 Wilmington, Delaware 19805 (US) (For All Designated States Except US).
DAL FARRA, Claude [FR/US]; (US) (For US Only).
DOMLOGE, Nouha [FR/FR]; (FR) (For US Only).
BOTTO, Jean-Marie [FR/FR]; (FR) (For US Only)
Inventors: DAL FARRA, Claude; (US).
DOMLOGE, Nouha; (FR).
BOTTO, Jean-Marie; (FR)
Agent: SOCIETE D´EXTRACTION DES PRINCIPES ACTIFS (ISP VINCIENCE); 655 Route du Pin Montard F-06410 Biot (FR)
Priority Data:
1100299 01.02.2011 FR
Title (EN) NOVEL PEPTIDES INVOLVED IN THE SCF C-KIT SIGNALLING PATHWAY AND COMPOSITIONS COMPRISING SAME
(FR) NOUVEAUX PEPTIDES INTERVENANT DANS LA VOIE DE SIGNALISATION SCF C-KIT ET COMPOSITIONS LES COMPRENANT
Abstract: front page image
(EN)The present invention relates to peptide compounds of general formula (I) R1-(AA)n-X1-X2-X3-Asp-Leu-Lys-Lys-X4-X5-(AA)P-R2. Said peptide compounds have an action on the SCF/c-Kit signalling pathway and thus make it possible to protect the pigmentary structures of the skin against external attacks. In addition, the present invention relates, firstly, to a cosmetic or pharmaceutical composition comprising at least one peptide of general formula (I), in a physiologically acceptable medium, and, secondly, to the use thereof for reducing age-related pigmentation defects and the effects of ageing on the skin. Finally, the invention relates to various cosmetic treatment processes using said peptides according to the invention.
(FR)La présente invention se rapporte à des composés peptidiques de formule générale (I) R1- (AA)n- X1- X2- X3 -Asp - Leu - Lys - Lys - X4- X5 - (AA)P - R2. Lesdits composés peptidiques ont une action sur la voie de signalisation de SCF/c-Kit et permettent ainsi de protéger les structures pigmentaires de la peau vis-à-vis des agressions extérieures. En outre, la présente invention concerne, d'une part, une composition cosmétique ou pharmaceutique, comprenant au moins un peptide de formule générale (I), dans un milieu physiologiquement acceptable et, d'autre part, son utilisation pour atténuer les défauts de pigmentation liés à l'âge et les effets du photovieillissement sur la peau. L'invention porte enfin sur divers procédés de traitement cosmétiques à l'aide desdits peptides selon l'invention.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: French (FR)
Filing Language: French (FR)