WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2012104386) ANTAGONISTS OF GRASP55 FOR USE AS A MEDICAMENT
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/104386    International Application No.:    PCT/EP2012/051793
Publication Date: 09.08.2012 International Filing Date: 02.02.2012
IPC:
C07K 14/47 (2006.01), C12N 15/113 (2010.01), A61K 48/00 (2006.01), C12Q 1/68 (2006.01)
Applicants: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) [FR/FR]; 101, Rue de Tolbiac F-75013 Paris (FR) (For All Designated States Except US).
UNIVERSITE DE LA MEDITERRANEE AIX-MARSEILLE II [FR/FR]; 58, boulevard Charles Livon F-13007 Marseille (FR) (For All Designated States Except US).
AURRAND-LIONS, Michel [FR/FR]; (FR) (For US Only).
ZARUBICA, Ana [ME/FR]; (FR) (For US Only)
Inventors: AURRAND-LIONS, Michel; (FR).
ZARUBICA, Ana; (FR)
Agent: BLOT, Philippe; Cabinet Lavoix 2, Place d'Estienne d'Orves F-75441 Paris Cedex 09 (FR)
Priority Data:
11305106.4 02.02.2011 EP
Title (EN) ANTAGONISTS OF GRASP55 FOR USE AS A MEDICAMENT
(FR) ANTAGONISTES DE GRASP55 À UTILISER COMME MÉDICAMENT
Abstract: front page image
(EN)The present invention concerns antagonists of the Golgi reassembly-stacking protein of 55 k Da (Grasp55), for use as a medicament, in particular for use in the treatment of cell adhesion molecules implicated diseases, notably, MCAM or JAMs implicated diseases. According to some embodiments, said antagonists of the Golgi reassembly-stacking protein of 55 k Da (Grasp55) may be used in the treatment of cancer, metastases, and inflammatory diseases. The present invention further provides methods for screening for compounds liable of treating or preventing such diseases.
(FR)Antagonistes de Grasp55 à utiliser comme médicament. L'invention concerne des antagonistes de Grasp de 55 k Da (Grasp55), à utiliser comme médicament, plus précisément à utiliser dans le traitement de maladies impliquant des molécules d'adhésion cellulaire, notamment des maladies impliquant MCAM ou JAM. Selon certains modes de réalisation, lesdits antagonistes de Grasp55 peuvent être utilisés dans le traitement du cancer, de métastases, et de maladies inflammatoires. L'invention concerne enfin des procédés permettant de cribler des composés pouvant traiter ou prévenir de telles maladies. Figure :7
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)