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1. (WO2012103520) METHODS AND COMPOSITIONS FOR MODULATING CYCLOPHILIN D
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/103520    International Application No.:    PCT/US2012/023030
Publication Date: 02.08.2012 International Filing Date: 27.01.2012
IPC:
C12N 15/113 (2010.01), A61K 38/13 (2006.01), A61K 31/713 (2006.01)
Applicants: BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA [--/US]; Varner Hall, 3835 Holdrege Street Lincoln, NE 68583-0745 (US) (For All Designated States Except US).
PADANILAM, Babu [US/US]; (US) (For US Only)
Inventors: PADANILAM, Babu; (US)
Agent: MERKEL, William K.; Marshall, Gerstein & Borun LLP 233 S. Wacker Drive 6300 Willis Tower Chicago, IL 60606-6357 (US)
Priority Data:
61/437,398 28.01.2011 US
Title (EN) METHODS AND COMPOSITIONS FOR MODULATING CYCLOPHILIN D
(FR) PROCÉDÉS ET COMPOSITIONS POUR MODULER LA CYCLOPHILINE D
Abstract: front page image
(EN)Methods and compositions for modulating cyclophilin D, e.g., at least one cyclophilin D biological activity, are provided. Modulation of cyclophilin D is useful in preventing or treating obesity, an overweight condition, or in accommodating a desire to lose weight as well as being useful in treating a variety of kidney diseases.
(FR)La présente invention concerne des procédés et des compositions pour moduler la cyclophiline D, par exemple, au moins une activité biologique de cyclophiline D. La modulation de la cyclophiline D est utile dans la prévention ou le traitement de l'obésité, un trouble de surpoids, ou dans la réponse à un souhait de perte de poids et est également utile dans le traitement de différentes maladies rénales.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)