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Pub. No.:    WO/2012/103353    International Application No.:    PCT/US2012/022753
Publication Date: 02.08.2012 International Filing Date: 26.01.2012
C12Q 1/68 (2006.01), C12Q 1/04 (2006.01), C12N 15/11 (2006.01)
Applicants: THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES [US/US]; Centers for Disease Control and Prevention Technology Transfer Office 4770 Buford Highway, MS K79 Atlanta, GA 30341 (US) (For All Designated States Except US).
THOMAS, Jennifer, Dolan [US/US]; (US) (For US Only).
WANG, Xin [US/US]; (US) (For US Only).
HATCHER, Cynthia [US/US]; (US) (For US Only).
ANDERSON, Raydel [US/US]; (US) (For US Only).
THEODORE, Mary, Jordan [US/US]; (US) (For US Only).
MAYER, Leonard, W. [US/US]; (US) (For US Only)
Inventors: THOMAS, Jennifer, Dolan; (US).
WANG, Xin; (US).
HATCHER, Cynthia; (US).
ANDERSON, Raydel; (US).
THEODORE, Mary, Jordan; (US).
MAYER, Leonard, W.; (US)
Agent: GOULD, Weston, R.; Gifford, Krass, Sprinkle, Anderson & Citkowski, P.C. 2701 Troy Center Drive, Suite 330 Post Office Box 7021 Troy, MI 48007-7021 (US)
Priority Data:
61/436,535 26.01.2011 US
Abstract: front page image
(EN)A process for detecting Haemophilus influenzae nucleic acid in a sample includes producing an amplification product by amplifying a Haemophilus influenzae nucleotide sequence and measuring the amplification product to detect Haemophilus influenzae in the sample. Some embodiments allow direct serotype determination in a single step assay. Also provided are reagents and methods for detecting and distinguishing Haemophilus influenzae from other infectious agents. A kit is provided for detecting and quantifying Haemophilus influenzae in a sample.
(FR)La présente invention concerne un procédé pour détecter de l'acide nucléique de Haemophilus influenzae dans un échantillon qui comprend la production d'un produit d'amplification par amplification d'une séquence nucléotidique de Haemophilus influenzae et mesure du produit d'amplification pour détecter Haemophilus influenzae dans l'échantillon. Certains modes de réalisation permettent la détermination de sérotype directe dans un dosage à une étape. La présente invention concerne en outre des réactifs et des procédés pour détecter et distinguer Haemophilus influenzae d'autres agents infectieux. La présente invention concerne en outre un kit pour détecter et quantifier Haemophilus influenzae dans un échantillon.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)