WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2012103345) COMPOSITIONS CONTAINING GLYCOSYLATED ANTIBODIES AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/103345    International Application No.:    PCT/US2012/022742
Publication Date: 02.08.2012 International Filing Date: 26.01.2012
Chapter 2 Demand Filed:    21.08.2012    
IPC:
C12P 21/08 (2006.01)
Applicants: ABBVIE INC. [US/US]; 1 North Waukegan Road North Chicago, Illinois 60064 (US) (For All Designated States Except US).
CORREIA, Ivan, R.S. [US/US]; (US) (For US Only).
FUJIMORI, Taro [US/US]; (US) (For US Only).
HRUSKA, Matthew, W. [US/US]; (US) (For US Only).
PAULSON, Susan, Kaye [US/US]; (US) (For US Only)
Inventors: CORREIA, Ivan, R.S.; (US).
FUJIMORI, Taro; (US).
HRUSKA, Matthew, W.; (US).
PAULSON, Susan, Kaye; (US)
Agent: ZACHARAKIS, Maria Laccotripe; McCarter & English, LLP 265 Franklin Street Boston, MA 02110 (US)
Priority Data:
61/437,107 28.01.2011 US
Title (EN) COMPOSITIONS CONTAINING GLYCOSYLATED ANTIBODIES AND USES THEREOF
(FR) COMPOSITIONS CONTENANT DES ANTICORPS GLYCOSYLÉS ET UTILISATIONS DE CELLES-CI
Abstract: front page image
(EN)The present invention provides compositions of antibodies, e.g., human antibodies, of varying glycosylation structures that serve to achieve desired rates of serum clearance. The invention also provides methods for modulating the pharmacokinetics of antibodies, e.g., human antibodies, and therapeutic compositions containing such antibodies. These methods rely on varying the glycosylation structures of the antibodies, e.g., human antibodies, to achieve desired rates of serum clearance.
(FR)La présente invention concerne des compositions d'anticorps, par exemple, d'anticorps humains, de structures de glycosylation variables qui servent à obtenir des taux souhaités de clairance sérique. L'invention concerne en outre des procédés pour moduler la pharmacocinétique d'anticorps, par exemple, d'anticorps humains, et des compositions thérapeutiques contenant de tels anticorps. Ces procédés reposent sur la variation des structures de glycosylation des anticorps, par exemple, des anticorps humains, pour obtenir des taux souhaités de clairance sérique.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)