US2012022721 TETRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME

1. (WO2012103333) TETRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME

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Latest bibliographic data on file with the International Bureau

Pub. No.:		WO/2012/103333		International Application No.:		PCT/US2012/022721
Publication Date:		02.08.2012		International Filing Date:		26.01.2012

IPC:

C07D 257/06 (2006.01), A61K 31/41 (2006.01), A61P 3/04 (2006.01)

Applicants:

ZAFGEN, INC. [US/US]; One Broadway, 8th Floor Cambridge, MA 02142 (US) (For All Designated States Except US).
DYKE, Hazel, Joan [GB/GB]; (GB) (For US Only).
PALLIN, Thomas, David [GB/GB]; (GB) (For US Only).
CRAMP, Susan, Mary [GB/GB]; (GB) (For US Only)

Inventors:

DYKE, Hazel, Joan; (GB).
PALLIN, Thomas, David; (GB).
CRAMP, Susan, Mary; (GB)

Agent:

KAVANAUGH, Theresa, C.; Goodwin Procter LLP Exchange Place Boston, MA 02109 (US)

Priority Data:

61/436,265

26.01.2011

Title

(EN) TETRAZOLE COMPOUNDS AND METHODS OF MAKING AND USING SAME
(FR) COMPOSÉS DE TÉTRAZOLE ET PROCÉDÉS DE PRÉPARATION ET D'UTILISATION DE CEUX-CI

Abstract:

(EN)Described herein are tetrazole compounds and their use in treating medical disorders, such as obesity. Pharmaceutical compositions and methods of making various tetrazole compounds are provided. The compounds are contemplated to have activity against methionyl aminopeptidase 2.
(FR)La présente invention concerne des composés de tétrazole et leur utilisation dans le traitement de troubles médicaux, tels que l'obésité. La présente invention concerne des compositions pharmaceutiques et des procédés de fabrication de différents composés de tétrazole. Il est envisagé que les composés aient une activité contre la méthionyle aminopeptidase 2.

Designated States:

AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).

Publication Language:	English (EN)
Filing Language:	English (EN)

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