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1. (WO2012103282) METHODS AND COMPOSITIONS FOR TREATING ALZHEIMER'S DISEASE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/103282    International Application No.:    PCT/US2012/022646
Publication Date: 02.08.2012 International Filing Date: 26.01.2012
IPC:
A61K 39/395 (2006.01), A61P 25/28 (2006.01), A61P 25/00 (2006.01)
Applicants: COLD SPRING HARBOR LABORATORY [US/US]; One Bungtown Road Cold Spring Harbor, NY 11724 (US) (For All Designated States Except US).
ZHONG, Yi [CN/US]; (US) (For US Only).
CHIANG, Hsueh-Cheng [--/US]; (US) (For US Only).
WANG, Lei [CN/CN]; (CN) (For US Only).
MA, Weiwei [CN/CN]; (CN) (For US Only)
Inventors: ZHONG, Yi; (US).
CHIANG, Hsueh-Cheng; (US).
WANG, Lei; (CN).
MA, Weiwei; (CN)
Agent: GROLZ, Edward W.; Scully, Scott, Murphy & Presser 400 Garden City Plaza Suite 300 Garden City, New York 11530 (US)
Priority Data:
61/436,363 26.01.2011 US
Title (EN) METHODS AND COMPOSITIONS FOR TREATING ALZHEIMER'S DISEASE
(FR) PROCÉDÉS ET COMPOSITIONS CONVENANT AU TRAITEMENT DE LA MALADIE D'ALZHEIMER
Abstract: front page image
(EN)This disclosure relates to methods and compositions useful for treating Alzheimer's disease. In particular, the disclosure relates to pharmaceutical compositions containing an EGFR-inhibitory compound suitable for administration to treat Alzheimer's disease, as well as to related therapeutic methods. In addition, this disclosure relates to screening methods for identifying compounds useful for treating Alzheimer's disease based on the ability to inhibit the activity of EGFR.
(FR)La présente invention concerne des procédés et des compositions convenant au traitement de la maladie d'Alzheimer. L'invention concerne plus particulièrement, d'une part des compositions pharmaceutiques contenant un composé inhibiteur du récepteur du facteur de croissance épithéliale ou "EGFR" (Epithelial Growth Factor Receptor) convenant à une administration destinée au traitement de la maladie d'Alzheimer, et d'autre part des procédés thérapeutiques correspondants. L'invention concerne en outre des procédés de recherche systématique permettant d'identifier des composés convenant au traitement de la maladie d'Alzheimer sur la base de leur aptitude à inhiber l'activité du récepteur EGFR.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)