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Machine translation
1. (WO2012103012) METHODS FOR GENERATING INNER EAR CELLS IN VITRO
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/103012    International Application No.:    PCT/US2012/022222
Publication Date: 02.08.2012 International Filing Date: 23.01.2012
IPC:
A61K 35/30 (2006.01), A61P 27/16 (2006.01), C12N 5/00 (2006.01)
Applicants: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY [US/US]; 1705 El Camino Real Palo Alto, California 94306-1106 (US) (For All Designated States Except US).
HELLER, Stefan [DE/US]; (US) (For US Only).
RONAGHI, Mohammad [IR/US]; (US) (For US Only).
OSHIMA, Kazuo [JP/US]; (US) (For US Only)
Inventors: HELLER, Stefan; (US).
RONAGHI, Mohammad; (US).
OSHIMA, Kazuo; (US)
Agent: ALCAMO, Elizabeth A.; Bozicevic, Field & Francis LLP 1900 University Avenue, Suite 200 East Palo Alto, California 94303 (US)
Priority Data:
61/435,541 24.01.2011 US
61/484,095 09.05.2011 US
Title (EN) METHODS FOR GENERATING INNER EAR CELLS IN VITRO
(FR) PROCÉDÉS DE GÉNÉRATION DE CELLULES DE L'OREILLE INTERNE IN VITRO
Abstract: front page image
(EN)Methods, compositions and kits are provided for generating inner ear cells in vitro. These methods find use a number of applications, such as in preparing inner ear cells for in vitro screening for agents that are toxic to inner ear cells, for in vitro screening for agents that prevent against, mitigate, or reverse the toxic effects of such agents, and for in vitro screening for agents that promote otoregeneration.
(FR)L'invention concerne des procédés, des compositions et des trousses qui sont utilisés pour générer des cellules de l'oreille interne in vitro. Ces procédés peuvent être utilisés dans un certain nombre d'applications, telles que la préparation de cellules de l'oreille interne dans un criblage in vitro d'agents qui sont toxiques aux cellules de l'oreille interne, dans le criblage in vitro d'agents qui préviennent, atténuent ou annulent les effets toxiques desdits agents toxiques, et dans le criblage in vitro d'agents qui favorisent la régénération des cellules de l'oreille interne.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)