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1. (WO2012101741) TIE-2 ACTIVATOR, AGENT FOR MATURATION, NORMALIZATION, OR STABILIZATION OF BLOOD VESSELS, LYMPH VESSEL STABILIZING AGENT, WRINKLE PREVENTION/IMPROVEMENT AGENT, AND EDEMA IMPROVEMENT/PREVENTION AGENT
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/101741    International Application No.:    PCT/JP2011/051234
Publication Date: 02.08.2012 International Filing Date: 24.01.2011
IPC:
A61K 36/48 (2006.01), A61K 8/97 (2006.01), A61K 36/00 (2006.01), A61K 36/18 (2006.01), A61K 36/42 (2006.01), A61K 36/896 (2006.01), A61P 9/14 (2006.01), A61P 17/00 (2006.01), A61P 43/00 (2006.01), A61Q 19/00 (2006.01)
Applicants: SHISEIDO COMPANY, LTD. [JP/JP]; 5-5, Ginza 7-chome, Chuo-ku, Tokyo 1048010 (JP) (For All Designated States Except US).
OTA, Masahiro [JP/JP]; (JP) (For US Only).
SAITO, Tomoko [JP/JP]; (JP) (For US Only)
Inventors: OTA, Masahiro; (JP).
SAITO, Tomoko; (JP)
Agent: AOKI, Atsushi; SEIWA PATENT & LAW, Toranomon 37 Mori Bldg., 5-1, Toranomon 3-chome, Minato-ku, Tokyo 1058423 (JP)
Priority Data:
Title (EN) TIE-2 ACTIVATOR, AGENT FOR MATURATION, NORMALIZATION, OR STABILIZATION OF BLOOD VESSELS, LYMPH VESSEL STABILIZING AGENT, WRINKLE PREVENTION/IMPROVEMENT AGENT, AND EDEMA IMPROVEMENT/PREVENTION AGENT
(FR) ACTIVATEUR DE TIE-2, AGENT POUR LA MATURATION, LA NORMALISATION, OU LA STABILISATION DE VAISSEAUX SANGUINS, AGENT DE STABILISATION DES VAISSEAUX LYMPHATIQUES, AGENT DE PRÉVENTION/AMÉLIORATION DES RIDES, ET AGENT D'AMÉLIORATION/PRÉVENTION DE L'ŒDÈME.
(JA) Tie2活性化剤、血管の成熟化、正常化又は安定化剤、リンパ管安定化剤並びにしわ防止・改善剤及びむくみ改善・予防剤
Abstract: front page image
(EN)The present invention provides: a tie-2 activator comprising the extracts of the stem branch or seed of sokakushi (Gleditsia sinensis Lam.), polygonatum rhizome (Polygonatum sibiricum Red.), Angular Solomon's Seal (Polygonatum officinalle), the fruit or seed of trichosanthes (Trichosanthes kirilowii Maxim), and/or Indian Mulberry (Morinda officinalis How.); an agent for maturation, normalization, or stabilization of blood vessels and a lymph vessel stabilizing agent; and a wrinkle prevention/improvement agent and edema improvement/prevention agent that are characterized by being a combination of the activator and agents.
(FR)La présente invention concerne : un activateur de TIE-2 comprenant les extraits de tige, branche ou graine de sokakushi (Gleditsia sinensis Lam.), rhizome de polygonatum (Polygonatum sibiricum Red.), sceau de Salomon (Polygonatum officinalle), fruit ou graine de Trichosanthes (Trichosanthes kirilowii Maxim), et/ou de pomme-chien (Morinda officinalis How.) ; un agent pour la maturation, la normalisation, ou la stabilisation de vaisseaux sanguins et un agent de stabilisation des vaisseaux lymphatiques ; et un agent de prévention/amélioration des rides et un agent d'amélioration/prévention de l'œdème qui sont caractérisés en ce qu'ils sont une combinaison de l'activateur et d'agents.
(JA) 本発明は、ソウカクシ[トウサイカチ(Gleditsia sinensis Lam.)の茎枝や種子]、オウセイ(Polygonatum sibiricum Red.)、ギョクチク(Polygonatum officinalle)、カロニン[シナカラスウリ(Trichosanthes kirilowii Maxim)の果実や種子]及び/又はハゲキテン(Morinda officinalis How.)の抽出物から成るTie2活性化剤、血管の成熟化、正常化若しくは安定化剤、リンパ管安定化剤、並びに前記剤を配合することを特徴とする、しわ防止・改善剤及びむくみ改善・予防剤を提供する。
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)