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1. (WO2012100835) METHODS AND COMPOSITIONS FOR THE TREATMENT OF AIDS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/100835    International Application No.:    PCT/EP2011/051237
Publication Date: 02.08.2012 International Filing Date: 28.01.2011
IPC:
A61K 31/164 (2006.01), A61P 31/18 (2006.01)
Applicants: LABORATORIOS DEL DR. ESTEVE, S.A. [ES/ES]; Avda. Mare de Déu de Montserrat, 221 E-08041 Barcelona (ES) (For All Designated States Except US).
FUNDACIÓ PRIVADA INSTITUT DE RECERCA DE LA SIDA-CAIXA [ES/ES]; Hospital Universitari Germans Trias i Pujol Carretera de Canyet, s/n E-08916 Badalona (ES) (For All Designated States Except US).
FABRIÀS DOMINGO, Gemma [ES/ES]; (ES) (For US Only).
GOÑI URCELAY, Félix [ES/ES]; (ES) (For US Only).
IZQUIERDO USEROS, Nuria [ES/ES]; (ES) (For US Only).
LLEBARIA SOLDEVILA, Amadeu [ES/ES]; (ES) (For US Only).
MAÑES BROTÓN, Santos [ES/ES]; (ES) (For US Only).
MARTÍNEZ PICADO, Javier [ES/ES]; (ES) (For US Only)
Inventors: FABRIÀS DOMINGO, Gemma; (ES).
GOÑI URCELAY, Félix; (ES).
IZQUIERDO USEROS, Nuria; (ES).
LLEBARIA SOLDEVILA, Amadeu; (ES).
MAÑES BROTÓN, Santos; (ES).
MARTÍNEZ PICADO, Javier; (ES)
Agent: ALCONADA RODRÍGUEZ, Agustín; ABG Patentes, S.L. Avenida de Burgos, 16D Edificio Euromor E-28036 Madrid (ES)
Priority Data:
Title (EN) METHODS AND COMPOSITIONS FOR THE TREATMENT OF AIDS
(FR) MÉTHODES ET COMPOSITIONS POUR LE TRAITEMENT DU SIDA
Abstract: front page image
(EN)The application relates to a method for the treatment of a disease caused by HIV infection by administering to a patient in need thereof of a specific inhibitor of the dehydroceramide desaturase. The invention relates as well to compositions comprising a Des-1inhibitor and one or more drugs suitable for the treatment of diseases caused by HIV infection as well as to methods for the identification of compounds suitable for the treatment of said diseases.
(FR)La présente invention concerne une méthode de traitement d'une maladie provoquée par une infection par le VIH, consistant à administrer à un patient en ayant besoin un inhibiteur spécifique de la dihydrocéramide désaturase. L'invention porte en outre sur des compositions comprenant un inhibiteur de Des-1, et un ou plusieurs médicaments adaptés au traitement de maladies provoquées par une infection par le VIH, ainsi que sur des méthodes d'identification de composés adaptés au traitement desdites maladies.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)