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1. WO2012099915 - THIAZOLIDINE DERIVATIVES AND THEIR THERAPEUTIC USE

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Publication Number WO/2012/099915
Publication Date 26.07.2012
International Application No. PCT/US2012/021637
International Filing Date 18.01.2012
IPC
A61K 31/496 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two nitrogen atoms as the only ring hetero atoms, e.g. piperazine
496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
CPC
A61K 31/496
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
395having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
495having six-membered rings with two ; or more; nitrogen atoms as the only ring heteroatoms, e.g. piperazine ; or tetrazines
496Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
A61K 45/06
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
45Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
C07D 403/12
CCHEMISTRY; METALLURGY
07ORGANIC CHEMISTRY
DHETEROCYCLIC COMPOUNDS
403Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
02containing two hetero rings
12linked by a chain containing hetero atoms as chain links
Applicants
  • ZHU, Hongwen [CN]/[US]
  • ZHANG, Qiang [CN]/[US]
Inventors
  • ZHU, Hongwen
  • ZHANG, Qiang
Agents
  • LIU, W. Jerry
Priority Data
61/434,15519.01.2011US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) THIAZOLIDINE DERIVATIVES AND THEIR THERAPEUTIC USE
(FR) DÉRIVÉS DE THIAZOLIDINE ET LEUR UTILISATION THÉRAPEUTIQUE
Abstract
(EN) This invention provides deuterated thiazolidine derivatives and compositions comprising these compounds, which are useful agents for the treatment of hyperglycemia diseases or disorders, in particular diabetes mellitus. The disclosure also provides a method of treating hyperglycemia diseases or disorders, in particular diabetes mellitus, using these deuterated thiazolidine derivatives.
(FR) L'invention concerne des dérivés de thiazolidine deutérés et des compositions comprenant ces composés, qui sont des agents utilisés dans le traitement de maladies ou troubles d'hyperglycémie, notamment le diabète sucré. L'invention concerne également une méthode permettant de traiter des maladies ou troubles d'hyperglycémie, notamment le diabète sucré, au moyen de ces dérivés de thiazolidine deutérés.
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