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1. (WO2012098207) USE OF BUBR1 AS A BIOMARKER OF DRUG RESPONSE TO FURAZANOBENZIMIDAZOLES
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/098207    International Application No.:    PCT/EP2012/050818
Publication Date: 26.07.2012 International Filing Date: 19.01.2012
IPC:
G01N 33/50 (2006.01), A61K 31/00 (2006.01)
Applicants: BASILEA PHARMACEUTICA AG [CH/CH]; Grenzacherstrasse 487 CH-4005 Basel (CH) (For All Designated States Except US).
LANE, Heidi Alexandra [CH/CH]; (CH) (For US Only).
BACHMANN, Felix [CH/CH]; (CH) (For US Only).
BREULEUX, Madlaina [CH/CH]; (CH) (For US Only).
BOUTROS, Michael [DE/DE]; (DE) (For US Only).
GILBERT, Daniel [CH/DE]; (DE) (For US Only).
ZHANG, Xian [DE/DE]; (DE) (For US Only)
Inventors: LANE, Heidi Alexandra; (CH).
BACHMANN, Felix; (CH).
BREULEUX, Madlaina; (CH).
BOUTROS, Michael; (DE).
GILBERT, Daniel; (DE).
ZHANG, Xian; (DE)
Agent: BOHEST AG; P.O. Box 160 CH-4003 Basel (CH)
Priority Data:
11151677.9 21.01.2011 EP
Title (EN) USE OF BUBR1 AS A BIOMARKER OF DRUG RESPONSE TO FURAZANOBENZIMIDAZOLES
(FR) UTILISATION DU BUBR1 COMME BIOMARQUEUR DE RÉPONSE MÉDICAMENTEUSE AUX FURAZANOBENZIMIDAZOLES
Abstract: front page image
(EN)Use of BUBR1 as a biomarker for predicting the response to a compound, preferably resistance of a disease such as cancer in a subject, wherein the compound is a furazanobenzimidazole compound of general formula (I).
(FR)L'invention concerne l'utilisation du BUBR1 comme biomarqueur pour prédire la réponse à un composé, de préférence la résistance à une maladie telle que le cancer chez un sujet, ledit composé étant un composé furazanobenzimidazolé de formule générale (I).
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)