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Pub. No.:    WO/2012/097744    International Application No.:    PCT/CN2012/070597
Publication Date: 26.07.2012 International Filing Date: 19.01.2012
C07D 209/08 (2006.01), C07D 209/10 (2006.01), C07D 231/56 (2006.01), A61K 31/404 (2006.01), A61K 31/416 (2006.01), A61P 3/00 (2006.01), A61P 9/04 (2006.01), A61P 9/06 (2006.01), A61P 9/12 (2006.01), A61P 13/12 (2006.01)
Applicants: MERCK SHARP & DOHME CORP. [US/US]; 126 East Lincoln Avenue Rahway, New Jersey 07065-0907 (US) (For All Designated States Except US).
CRESPO, Alejandro [AR/US]; (US) (For US Only).
LAN, Ping [CN/US]; (US) (For US Only).
MAL, Rudrajit [US/US]; (US) (For US Only).
OGAWA, Anthony [US/US]; (US) (For US Only).
SHEN, Hong [US/US]; (US) (For US Only).
SINCLAIR, Peter J. [US/US]; (US) (For US Only).
SUN, Zhongxiang [CN/US]; (US) (For US Only).
BUNTE, Ellen K. Vande [US/US]; (US) (For US Only).
WU, Zhicai [US/US]; (US) (For US Only).
LIU, Kun [US/US]; (US) (For US Only).
DEVITA, Robert J. [US/US]; (US) (For US Only).
SHEN, Dong-Ming [US/US]; (US) (For US Only).
SHU, Min [US/US]; (US) (For US Only).
TAN, John Qiang [US/US]; (US) (For US Only).
QI, Changhe [CN/CN]; (CN) (For US Only).
WANG, Yuguang [US/US]; (US) (For US Only).
BERESIS, Richard [US/CN]; (CN) (For US Only)
Inventors: CRESPO, Alejandro; (US).
LAN, Ping; (US).
MAL, Rudrajit; (US).
OGAWA, Anthony; (US).
SHEN, Hong; (US).
SINCLAIR, Peter J.; (US).
SUN, Zhongxiang; (US).
BUNTE, Ellen K. Vande; (US).
WU, Zhicai; (US).
LIU, Kun; (US).
DEVITA, Robert J.; (US).
SHEN, Dong-Ming; (US).
SHU, Min; (US).
TAN, John Qiang; (US).
QI, Changhe; (CN).
WANG, Yuguang; (US).
BERESIS, Richard; (CN)
Agent: LIU, SHEN & ASSOCIATES; A0601, Huibin Building No. 8 Beichen Dong Street Chaoyang District Beijing 100101 (CN)
Priority Data:
61/434,543 20.01.2011 US
Abstract: front page image
(EN)Disclosed are the compounds of the Formula (I) as well as pharmaceutically acceptable salts thereof, which are useful for treating aldosterone-mediated diseases. The processes for preparing compounds of the Formula (I), the use for the therapy and prophylaxis of the abovementioned diseases and for preparing pharmaceuticals for this purpose, and the pharmaceutical compositions which comprise compounds of the formula (I) are disclosed too.
(FR)L'invention concerne les composés de la Formule (I) ainsi que leurs sels pharmaceutiquement acceptables, qui sont utiles pour le traitement de maladies à médiation par l'aldostérone. L'invention concerne également les procédés de préparation de composés de la Formule (I), l'utilisation pour la thérapie et la prophylaxie des maladies mentionnées ci-dessus et pour préparer des médicaments dans ce but et les compositions pharmaceutiques qui comprennent des composés de la Formule (I).
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)