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Machine translation
1. (WO2012097454) COMPOUNDS FOR USE IN THE TREATMENT OF BACTERIAL INFECTION
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/097454    International Application No.:    PCT/CA2012/050029
Publication Date: 26.07.2012 International Filing Date: 17.01.2012
IPC:
C07H 15/224 (2006.01), A61K 31/7036 (2006.01), A61P 31/04 (2006.01), C07H 15/222 (2006.01)
Applicants: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING / MCGILL UNIVERSITY [CA/CA]; 845 Sherbrooke Street West Montréal, Québec H3A 2T5 (CA) (For All Designated States Except US).
AUCLAIR, Karine [CA/CA]; (CA) (For US Only).
VONG, Kenward [CA/CA]; (CA) (For US Only)
Inventors: AUCLAIR, Karine; (CA).
VONG, Kenward; (CA)
Agent: NORTON ROSE FULBRIGHT CANADA LLP/S.E.N.C.R.L., S.R.L.; Suite 2500 1 place Ville-Marie Montreal, Québec H3B 1R1 (CA)
Priority Data:
61/433,548 18.01.2011 US
Title (EN) COMPOUNDS FOR USE IN THE TREATMENT OF BACTERIAL INFECTION
(FR) COMPOSÉS UTILISÉS POUR TRAITER UNE INFECTION BACTÉRIENNE
Abstract: front page image
(EN)This invention relates to a compound of Formula 1A: or a pharmaceutically acceptable salt thereof: wherein R1 to R4. R7, R9 to R12 and Y are as defined herein. The invention further relates to pharmaceutical composition comprising said compound or a pharmaceutically acceptable salt thereof; and method of using same for reducing or reversing bacterial resistance to at least one aminoglycoside antibiotic.
(FR)L'invention concerne un composé représenté par la formule 1A ou un sel de celui-ci pharmaceutiquement acceptable. Dans la formule 1A, R1 à R4, R7, R9 à R12 et Y sont tels que définis dans la spécification. L'invention concerne également une composition pharmaceutique comprenant le composé ou son sel pharmaceutiquement acceptable; et une méthode utilisant le composé pour réduire ou inverser la résistance bactérienne à au moins un antibiotique aminoglycoside.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)