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1. (WO2012097353) METHODS, COMPOSITIONS, AND KITS FOR DETECTING RARE CELLS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/097353    International Application No.:    PCT/US2012/021397
Publication Date: 19.07.2012 International Filing Date: 14.01.2012
IPC:
C12Q 1/68 (2006.01), G01N 33/50 (2006.01)
Applicants: LIFE TECHNOLOGIES CORPORATION [US/US]; 5791 Van Allen Way Carlsbad, California 92008 (US) (For All Designated States Except US).
DENG, David Xingfei [US/US]; (US) (For US Only).
CHEN, Caifu [US/US]; (US) (For US Only)
Inventors: DENG, David Xingfei; (US).
CHEN, Caifu; (US)
Agent: PERFECT, Bernadette M.; Life Technologies Corporation 5791 Van Allen Way Carlsbad, California 92008 (US)
Priority Data:
61/433,146 14.01.2011 US
Title (EN) METHODS, COMPOSITIONS, AND KITS FOR DETECTING RARE CELLS
(FR) PROCÉDÉS, COMPOSITIONS ET TROUSSES POUR DÉTECTER DES CELLULES RARES
Abstract: front page image
(EN)Disclosed herein are methods for identifying rare cells containing particular markers and/or alleles from biological samples that have not been substantially pre-processed (e.g., unprocessed whole blood). The methods described herein provide a system for digital enrichment of target cells from a biological sample and detection of such target cells, thereby allowing accurate and efficient detection and / or enumeration of such cells in the sample.
(FR)La présente invention porte sur des procédés d'identification de cellules rares contenant des marqueurs et/ou des allèles particuliers provenant d'échantillons biologiques qui n'ont pas été sensiblement prétraités (par exemple, du sang total non traité). Les procédés décrits présentement fournissent un système pour un enrichissement numérique de cellules cibles provenant d'un échantillon biologique et une détection de telles cellules cibles, permettant ainsi une détection précise et efficace et/ou un dénombrement précis et efficace de telles cellules dans l'échantillon.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)