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1. (WO2012097117) GENOME ASSEMBLY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/097117    International Application No.:    PCT/US2012/021020
Publication Date: 19.07.2012 International Filing Date: 12.01.2012
C12Q 1/68 (2006.01)
Applicants: OPGEN, INC. [US/US]; 708 Quince Orchard Rd. Gaithersburg, MD 20878 (US) (For All Designated States Except US).
XIAO, Nianqing [US/US]; (US) (For US Only).
HENKHAUS, John, K. [US/US]; (US) (For US Only).
ZHU, Bin [CN/US]; (US) (For US Only).
SWEENEY, Deacon [US/US]; (US) (For US Only).
ANANTHARAMAN, Thomas [US/US]; (US) (For US Only).
PTASHKIN, Ryan, Nathan [US/US]; (US) (For US Only)
Inventors: XIAO, Nianqing; (US).
HENKHAUS, John, K.; (US).
ZHU, Bin; (US).
SWEENEY, Deacon; (US).
PTASHKIN, Ryan, Nathan; (US)
Agent: MEYERS, Thomas, C.; Brown Rudnick LLP One Financial Center Boston, MA 02111 (US)
Priority Data:
61/432,828 14.01.2011 US
13/096,408 28.04.2011 US
Abstract: front page image
(EN)The invention generally relates to methods for assembling sequence contigs. In certain embodiments, methods of the invention involve converting sequence contigs into maps, generating a plurality of single molecule restriction maps, aligning single molecule restriction maps to ends of the maps of the sequence contigs, thereby producing extended sequence contigs, and aligning extended sequence contigs.
(FR)La présente invention concerne de façon générale des méthodes d'assemblage de contigs de séquences. Dans certains modes de réalisation, les méthodes selon l'invention impliquent la conversion de contigs de séquences en cartes, générant une multitude de cartes de restriction à une seule molécule, l'alignement des cartes de restriction à une seule molécule aux extrémités des cartes des contigs de séquences pour obtenir des contigs de séquences étendus, et l'alignement des contigs de séquences étendus.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)