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Pub. No.:    WO/2012/097081    International Application No.:    PCT/US2012/020965
Publication Date: 19.07.2012 International Filing Date: 11.01.2012
G01N 27/30 (2006.01), G01N 33/483 (2006.01)
Applicants: THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO [CA/CA]; 27 King's College Circle Toronto, Ontario M5S 1A1 (CA) (For All Designated States Except US).
DAS, Jagotamoy [BD/CA]; (CA) (For US Only).
KELLEY, Shana, O. [US/CA]; (CA) (For US Only)
Inventors: DAS, Jagotamoy; (CA).
KELLEY, Shana, O.; (CA)
Agent: LARSEN, Charles, D.; Ropes & Gray LLP Prudential Tower 800 Boylston Street Boston, MA 02199 (US)
Priority Data:
61/431,786 11.01.2011 US
Abstract: front page image
(EN)Described herein are systems and methods for detecting a target analyte in a sample with electrodes, comprising a linker and an antibody attached to the linker, and measuring an electrocatalytic signal changes generated by binding of an analyte in the sample to the antibody. Also disclosed herein are kits for electrochemical detection of protein analytes.
(FR)La présente invention concerne des systèmes et des procédés de détection d'une substance à analyser cible dans un échantillon, à l'aide d'électrodes, comportant un liant et un anticorps fixé au liant, et de mesure de modifications de signal électrocatalytique générées par la liaison d'une substance à analyser à l'anticorps dans l'échantillon. La présente invention concerne également des nécessaires pour la détection électrochimique de substances à analyser protéiques.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)