WIPO logo
Mobile | Deutsch | Español | Français | 日本語 | 한국어 | Português | Русский | 中文 | العربية |
PATENTSCOPE

Search International and National Patent Collections
World Intellectual Property Organization
Search
 
Browse
 
Translate
 
Options
 
News
 
Login
 
Help
 
Machine translation
1. (WO2012097013) IRAK INHIBITORS AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/097013    International Application No.:    PCT/US2012/020845
Publication Date: 19.07.2012 International Filing Date: 10.01.2012
IPC:
A61K 31/519 (2006.01), C07D 495/02 (2006.01)
Applicants: NIMBUS IRIS, INC. [US/US]; 25 First Street, Suite 303 Cambridge, MA 02142 (US) (For All Designated States Except US).
ROMERO, Donna L. [US/US]; (US) (For US Only).
WESSEL, Matthew David [US/US]; (US) (For US Only).
ROBINSON, Shaughnessy [US/US]; (US) (For US Only).
GREENWOOD, Jeremy Robert [AU/US]; (US) (For US Only).
WATTS, Karl Shawn [US/US]; (US) (For US Only).
FRYE, Leah Lynn [US/US]; (US) (For US Only).
HARRIMAN, Geraldine C. [US/US]; (US) (For US Only).
CORIN, Alan Franklin [US/US]; (US) (For US Only).
MASSE, Craig [US/US]; (US) (For US Only).
SHELLEY, Mee [US/US]; (US) (For US Only)
Inventors: ROMERO, Donna L.; (US).
WESSEL, Matthew David; (US).
ROBINSON, Shaughnessy; (US).
GREENWOOD, Jeremy Robert; (US).
WATTS, Karl Shawn; (US).
FRYE, Leah Lynn; (US).
HARRIMAN, Geraldine C.; (US).
CORIN, Alan Franklin; (US).
MASSE, Craig; (US).
SHELLEY, Mee; (US)
Agent: ROBIDOUX, Andrea L.C.; Choate, Hall & Stewart LLP Two International Place Boston, MA 02110 (US)
Priority Data:
61/545,873 11.10.2011 US
61/431,227 10.01.2011 US
Title (EN) IRAK INHIBITORS AND USES THEREOF
(FR) INHIBITEURS D'IRAK ET LEURS UTILISATION
Abstract: front page image
(EN)The present invention relates to compounds and methods useful for inhibiting one or more interleukin-l receptor-associated kinases ("IRAK"). In some embodiments, a provided compound inhibits IRAK-1 and IRAK-4. The invention also provides pharmaceutically acceptable compositions comprising compounds of the present invention and methods of using said compositions in the treatment of various disorders.
(FR)L'invention concerne des composés et des méthodes utiles pour l'inhibition d'une ou plusieurs kinases associées au récepteur de l'interleukine I ("IRAK"). Dans certains modes de réalisation, un composé divulgué inhibe IRAK-1 et IRAK-4. L'invention porte également sur des compositions de qualité pharmaceutique comprenant des composés de l'invention ainsi que sur des méthodes d'utilisation desdites compositions dans le traitement de divers troubles.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)