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1. (WO2012095527) METHODS AND REAGENTS FOR EFFICIENT AND TARGETED DELIVERY OF THERAPEUTIC MOLECULES TO CXCR4 CELLS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/095527    International Application No.:    PCT/EP2012/050513
Publication Date: 19.07.2012 International Filing Date: 13.01.2012
IPC:
A61K 47/48 (2006.01), C07K 14/435 (2006.01), C12N 15/62 (2006.01)
Applicants: UNIVERSITAT AUTONOMA DE BARCELONA [ES/ES]; Edifici A Campus universitari s/n E-08193 Bellaterra (Cerdanyola del Valles) (ES) (For All Designated States Except US).
INSTITUT RECERCA HOSPITAL DE LA SANTA CREU I SANT PAU [ES/ES]; Hospital de Sant Pau C/Sant Antoni Maria Claret 167 E-08025 Barcelona (ES) (For All Designated States Except US).
CENTRO INVESTIGACIÓN BIOMÉDICA EN RED (CIBER BBN) [ES/ES]; Edificio I+D Campus Río Ebro - Edificio I+D - Pta. 1ª, Bloq. 5 C/Poeta Mariano Esquillor, s/n E-50018 Zaragoza (ES) (For All Designated States Except US).
VILLAVERDE CORRALES, Antonio [ES/ES]; (ES) (For US Only).
VÁZQUEZ GÓMEZ, Esther [ES/ES]; (ES) (For US Only).
CÉSPEDES NAVARRO, María Virtudes [ES/ES]; (ES) (For US Only).
CASANOVA RIGAT, Isolda [ES/ES]; (ES) (For US Only).
FERRER MIRALLES, Neus [ES/ES]; (ES) (For US Only).
MANGUES BAFALLUY, Ramon [ES/ES]; (ES) (For US Only).
UNZUETA ELORZA, Ugutz [ES/ES]; (ES) (For US Only)
Inventors: VILLAVERDE CORRALES, Antonio; (ES).
VÁZQUEZ GÓMEZ, Esther; (ES).
CÉSPEDES NAVARRO, María Virtudes; (ES).
CASANOVA RIGAT, Isolda; (ES).
FERRER MIRALLES, Neus; (ES).
MANGUES BAFALLUY, Ramon; (ES).
UNZUETA ELORZA, Ugutz; (ES)
Priority Data:
11382005.4 13.01.2011 EP
Title (EN) METHODS AND REAGENTS FOR EFFICIENT AND TARGETED DELIVERY OF THERAPEUTIC MOLECULES TO CXCR4 CELLS
(FR) PROCÉDÉS ET RÉACTIFS POUR LA LIVRAISON EFFICACE ET CIBLÉE DE MOLÉCULES THÉRAPEUTIQUES AUX CELLULES CXCR4
Abstract: front page image
(EN)The invention relates to conjugates comprising a targeting moiety specific for the CXCR4 based on the polyphemusin-derived peptide and a therapeutic or imaging agent. The invention relates as well to the application of said conjugates for the therapy and diagnostics which require the specific targeting to CXCR4+ cells.
(FR)L'invention concerne des conjugués comprenant une partie ciblante spécifique des CXCR4 basée sur un peptide dérivé de la polyphémusine et un agent thérapeutique ou d'imagerie. L'invention concerne aussi l'application desdits conjugués pour le traitement et les diagnostics qui nécessitent le ciblage spécifique des cellules CXCR4+.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)