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1. (WO2012095281) AMINO ACID COMPOSITION AND ITS USE FOR TREATING INTRAUTERINE FOETAL GROWTH RESTRICTION (IUGR) OR FOR PARENTERAL NUTRITION OF EXTREMELY PRE-TERM INFANTS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2012/095281 International Application No.: PCT/EP2012/000045
Publication Date: 19.07.2012 International Filing Date: 06.01.2012
IPC:
A61P 15/06 (2006.01) ,A23L 1/305 (2006.01) ,A61K 31/198 (2006.01) ,A61P 43/00 (2006.01)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
15
Drugs for genital or sexual disorders; Contraceptives
06
Antiabortive agents; Labour repressants
A HUMAN NECESSITIES
23
FOODS OR FOODSTUFFS; THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
L
FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D91; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
1
Foods or foodstuffs; Their preparation or treatment
29
Modifying nutritive qualities of foods; Dietetic products
30
containing additives
305
Amino acids, peptides or proteins 
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31
Medicinal preparations containing organic active ingredients
185
Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
19
Carboxylic acids, e.g. valproic acid
195
having an amino group
197
the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid (GABA), beta-alanine, epsilon-aminocaproic acid, pantothenic acid
198
Alpha-amino acids, e.g. alanine, edetic acid (EDTA)
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43
Drugs for specific purposes, not provided for in groups A61P1/-A61P41/108
Applicants:
TCHIRIKOV, Michael [RU/DE]; DE
Inventors:
TCHIRIKOV, Michael; DE
Agent:
PATENTANWÄLTE BITTERICH, DR. KELLER, SCHWERTFEGER; Westring 17 76829 Landau/Pfalz, DE
Priority Data:
11000211.013.01.2011EP
Title (DE) AMINOSÄUREZUSAMMENSETZUNG UND DEREN VERWENDUNG ZUR BEHANDLUNG VON INTRAUTERINER FETALER WACHSTUMSRESTRIKTION (IUGR) ODER ZUR PARENTERALEN ERNÄHRUNG VON EXTREM FRÜHGEBORENEN
(EN) AMINO ACID COMPOSITION AND ITS USE FOR TREATING INTRAUTERINE FOETAL GROWTH RESTRICTION (IUGR) OR FOR PARENTERAL NUTRITION OF EXTREMELY PRE-TERM INFANTS
(FR) COMPOSITION D'ACIDES AMINÉS ET SON UTILISATION POUR LE TRAITEMENT DE LA RESTRICTION DE CROISSANCE FŒTALE INTRA-UTÉRINE (IUGR) OU POUR L'ALIMENTATION PARENTÉRALE DE PRÉMATURÉS EXTRÊMES
Abstract:
(DE) Die Erfindung betrifft eine Zusammensetzung für die Verwendung zur Behandlung einer fetalen Wachstumsrestriktion (IUGR) oder zur parenteralen Ernährung von extrem Frühgeborenen in der 24. bis 34. Schwangerschaftswoche. Die Zusammensetzung umfasst eine Mischung aus Aminosäuren oder deren künstliche oder modifizierte Aminosäureanaloge oder Substitute, ausgewählt aus der Gruppe bestehend aus: Isoleucin, Leucin, Lysin, Methionin, Phenylalanin, Threonin, Tryptophan, Valin, Arginin, Histidin, Ornithin, Glycin, Alanin, Prolin, Aspartat, Asparagin, Glutamat, Glutamin, Serin, Tyrosin, Taurin, Hydroxyprolin, Citrullin, Cystein. Die in der Lösung enthaltenen Aminosäuren liegen in Konzentrationen oder Konzentrationsverhältnissen vor, die den physiologischen Aminosäurenkonzentrationen oder Konzentrationsverhältnissen im Blutplasma eines gesunden Fötus in utero in der 24. bis 34. Schwangerschaftswoche entsprechen oder möglichst nahe kommen.
(EN) The invention relates to a composition for use in the treatment of foetal growth restriction (IUGR) or for parenteral nutrition of infants born extremely pre-term, in weeks 24 to 34 of pregnancy. The composition comprises a mixture of amino acids or their synthetic or modified amino acid analogues or substitutes, selected from the group of the following: isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan, valine, arginine, histidine, ornithine, glycine, alanine, proline, aspartate, asparagine, glutamate, glutamine, serine, tyrosine, taurine, hydroxyproline, citrulline, cysteine. The amino acids present in the solution are present at concentrations or in concentration ratios which correspond or come extremely close to the physiological amino acid concentrations or concentration ratios in the blood plasma of a healthy foetus in utero in weeks 24 to 34 of pregnancy.
(FR) L'invention concerne une composition à utiliser pour le traitement d'une restriction de croissance fœtale (IUGR) ou pour l'alimentation parentérale de prématurés extrêmes entre la 24e et la 34e semaine de grossesse. La composition comprend un mélange d'acides aminés ou de leurs analogues ou substituts synthétiques ou modifiés, sélectionnés dans le groupe consistant en: isoleucine, leucine, lysine, méthionine, phénylalanine, thréonine, tryptophane, valine, arginine, histidine, ornithine, glycine, alanine, proline, aspartate, asparagine, glutamate, glutamine, sérine, tyrosine, taurine, hydroxyproline, citrulline, cystéine. Les acides aminés contenus dans la solution sont présents dans des concentrations ou des rapports de concentration qui correspondent aux concentrations physiologiques d'acides aminés ou aux rapports de concentration dans le plasma sanguin d'un fétus sain in utero entre la 24e et la 34e semaine de grossesse ou s'en approchent autant que possible.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: German (DE)
Filing Language: German (DE)
Also published as:
EP2663366EA201391034