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1. (WO2012094623) ANTI-IL-12/IL-23 ANTIBODIES AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/094623    International Application No.:    PCT/US2012/020529
Publication Date: 12.07.2012 International Filing Date: 06.01.2012
Chapter 2 Demand Filed:    02.08.2012    
IPC:
C07K 16/24 (2006.01), A61K 39/395 (2006.01)
Applicants: ABBVIE Inc. [US/US]; 1 North Waukegan Road North Chicago, Illinois 60064 (US) (For All Designated States Except US).
BORHANI, David, W. [US/US]; (US) (For US Only).
SADHUKHAN, Ramkrishna [US/US]; (US) (For US Only).
LACY, Susan, E. [CA/US]; (US) (For US Only).
SOUTTER, Holly, H. [US/US]; (US) (For US Only)
Inventors: BORHANI, David, W.; (US).
SADHUKHAN, Ramkrishna; (US).
LACY, Susan, E.; (US).
SOUTTER, Holly, H.; (US)
Agent: ZACHARAKIS, Maria, Laccotripe; McCarter & English, LLP 265 Franklin Street Boston, MA 02110 (US)
Priority Data:
61/460,780 07.01.2011 US
Title (EN) ANTI-IL-12/IL-23 ANTIBODIES AND USES THEREOF
(FR) ANTICORPS ANTI-IL-12/IL-23 ET LEURS UTILISATIONS
Abstract: front page image
(EN)The present invention provides antibodies, and antigen-binding portions thereof, that bind to epitopes comprising at least one amino acid residues from residues 1-197 of the p40 subunit of IL-12 and/or IL-23. The invention further provides nucleic acids encoding the antibodies, compositions, vectors and host cells comprising the antibodies, and methods of making and using the same.
(FR)La présente invention concerne des anticorps et des parties liant l'antigène de ceux-ci, qui se lient aux déterminants antigéniques comprenant au moins un résidu d'acide aminé choisi parmi les résidus 1 à 197 de la sous-unité p40 de l'IL-12 et/ou de l'IL-23. L'invention concerne également des acides nucléiques codant pour lesdits anticorps, des compositions, des vecteurs et des cellules hôtes contenant lesdits anticorps, ainsi que des procédés de fabrication et d'utilisation de ceux-ci.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)