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1. (WO2012094511) COMPOSITIONS AND METHODS FOR THE TREATMENT OF ORTHOPEDIC DISEASE OR INJURY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/094511    International Application No.:    PCT/US2012/020353
Publication Date: 12.07.2012 International Filing Date: 05.01.2012
IPC:
A61K 48/00 (2006.01), A61K 47/42 (2006.01), A61K 47/48 (2006.01), C07K 19/00 (2006.01), C12N 15/863 (2006.01), A61P 19/02 (2006.01)
Applicants: RHODE ISLAND HOSPITAL [US/US]; 593 Eddy Street Providence, RI 02903 (US) (For All Designated States Except US).
CHEN, Qian [US/US]; (US) (For US Only).
JAYASURIYA, Chathuraka, T. [US/US]; (US) (For US Only)
Inventors: CHEN, Qian; (US).
JAYASURIYA, Chathuraka, T.; (US)
Agent: BEATTIE, Ingrid, A.; Mintz Levin Cohn Ferris Glovsky and Popeo, P.C. One Financial Center Boston, MA 02111 (US)
Priority Data:
61/430,134 05.01.2011 US
Title (EN) COMPOSITIONS AND METHODS FOR THE TREATMENT OF ORTHOPEDIC DISEASE OR INJURY
(FR) COMPOSITIONS ET PROCÉDÉS DESTINÉS AU TRAITEMENT DE LÉSION OU DE MALADIE ORTHOPÉDIQUE
Abstract: front page image
(EN)Methods for reducing the severity of an arthritic condition or repairing an osteochondral defect are carried out by administering to a subject compositions comprising a member of the matrilin family of proteins, e.g., a matrilin protein, fragment thereof, or nucleic acid encoding the protein or fragment.
(FR)La présente invention concerne des procédés de réduction de la gravité d'une affection arthritique ou de réparation d'un défaut ostéo-cartilagineux, réalisés par l'administration à un sujet de compositions comprenant un élément de la famille des matrilines, par exemple une protéine matriline, un fragment de celle-ci ou un acide nucléique codant pour ladite protéine ou ledit fragment.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)