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1. WO2012093738 - COMPOSITION FOR COMBATING OXIDATION AND ALLEVIATING DETRIMENTAL EFFECTS ON SKIN CAUSED BY ASIAN DUST

Publication Number WO/2012/093738
Publication Date 12.07.2012
International Application No. PCT/KR2011/000010
International Filing Date 03.01.2011
IPC
A61K 36/58 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
58Meliaceae (Chinaberry or Mahogany family), e.g. Azadirachta (neem)
A61K 36/62 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
62Nymphaeaceae (Water-lily family)
A61K 8/97 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
96containing materials, or derivatives thereof, of undetermined constitution
97from algae, fungi, lichens or plants; from derivatives thereof
A61P 17/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
17Drugs for dermatological disorders
A61P 39/06 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
39General protective or antinoxious agents
06Free radical scavengers or antioxidants
A61Q 19/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
QSPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
19Preparations for care of the skin
CPC
A23L 33/105
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A23B - A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT
33Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
10using additives
105Plant extracts, their artificial duplicates or their derivatives
A23V 2002/00
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES
2002Food compositions, function of food ingredients or processes for food or foodstuffs
A23V 2200/318
AHUMAN NECESSITIES
23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES
2200Function of food ingredients
30Foods, ingredients or supplements having a functional effect on health
318having an effect on skin health and hair or coat
A61K 36/58
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
58Meliaceae (Chinaberry or Mahogany family), e.g. Azadirachta (neem)
A61K 36/62
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
36Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
18Magnoliophyta (angiosperms)
185Magnoliopsida (dicotyledons)
62Nymphaeaceae (Water-lily family)
A61K 8/9789
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
96containing materials, or derivatives thereof of undetermined constitution
97from algae, fungi, lichens or plants; from derivatives thereof
9783Angiosperms [Magnoliophyta]
9789Magnoliopsida [dicotyledons]
Applicants
  • (주)아모레퍼시픽 AMOREPACIFIC CORPORATION [KR]/[KR] (AllExceptUS)
  • 최현 CHOI, Hyun [KR]/[KR] (UsOnly)
  • 김선미 KIM, Sun Mi [KR]/[KR] (UsOnly)
  • 문성호 MOON, Sung Ho [KR]/[KR] (UsOnly)
  • 임형준 LIM, Hyung Jun [KR]/[KR] (UsOnly)
  • 김지현 KIM, Ji Hyun [KR]/[KR] (UsOnly)
  • 이태룡 LEE, Tae Ryong [KR]/[KR] (UsOnly)
  • 신동욱 SHIN, Dong Wook [KR]/[KR] (UsOnly)
  • 강학희 KANG, Hak Hee [KR]/[KR] (UsOnly)
Inventors
  • 최현 CHOI, Hyun
  • 김선미 KIM, Sun Mi
  • 문성호 MOON, Sung Ho
  • 임형준 LIM, Hyung Jun
  • 김지현 KIM, Ji Hyun
  • 이태룡 LEE, Tae Ryong
  • 신동욱 SHIN, Dong Wook
  • 강학희 KANG, Hak Hee
Agents
  • 김순영 KIM, Sun-young
Priority Data
Publication Language Korean (KO)
Filing Language Korean (KO)
Designated States
Title
(EN) COMPOSITION FOR COMBATING OXIDATION AND ALLEVIATING DETRIMENTAL EFFECTS ON SKIN CAUSED BY ASIAN DUST
(FR) COMPOSITION POUR COMBATTRE L'OXYDATION ET DIMINUER LES EFFETS CUTANÉS INDÉSIRABLES PROVOQUÉS PAR LA POUSSIÈRE D'ASIE
(KO) 항산화용 및 황사에 의한 피부 유해영향 완화용 조성물
Abstract
(EN)
The present invention relates to a composition for combating oxidation and alleviating the detrimental effects on skin caused by Asian Dust, the composition containing Melia azedarach bark and Nelumbo nucifera leaf extracts as a novel skin irritation alleviating agent. More specifically, the present invention contains Melia azedarach bark and Nelumbo nucifera leaf extracts, and entails: detoxification and expulsion of toxins by increasing the expression of NQO1 which is an enzyme that detoxifies toxins and of GSTT1 which is an enzyme that expels toxins; protection of the skin by increasing the expression of the skin antimicrobial peptide hBD3 which is a natural immune factor; and suppression of the production of active oxygen by increasing expression of the antioxidant proteins GPX1, catalase, Trx1 and Prdx1. Consequently, the invention has the advantages of skin protection and ageing suppression.
(FR)
La présente invention concerne une composition pour combattre l'oxydation et pour diminuer les effets cutanés indésirables provoqués par la poussière d'Asie, la composition contenant de l'écorce de Melia azedarach et des extraits de feuilles de Nelumbo nucifera en tant que nouvel agent diminuant l'irritation cutanée. Plus particulièrement, la présente invention contient de l'écorce de Melia azedarach et des extraits de feuilles de Nelumbo nucifera et permet : la détoxication et l'expulsion de toxines par l'augmentation de l'expression de NQO1, qui est une enzyme qui détoxique les toxines, et de GFTT1, qui est une enzyme qui expulse les toxines ; la protection de la peau par l'augmentation de l'expression du peptide hBD3 antimicrobien cutané qui est un facteur immunitaire naturel ; la suppression de la production d'oxygène actif par l'augmentation de l'expression des protéines anti-oxydantes GPX1, catalase, Trx1 et Prdx1. L'invention présente donc les avantages d'une protection cutanée et de l'inhibition du vieillissement.
(KO)
본 발명은 새로운 피부자극 완화제로서 고련피 및 연꽃잎 추출물을 함유하는 항산화용 및 황사에 의한 피부 유해영향 완화용 조성물에 관한 것이다. 구체적으로, 본 발명은 고련피 및 연꽃잎 추출물을 함유하여, 독소를 해독하는 효소인 NQO1, 독소를 배출하는 효소인 GSTT1의 발현을 증가시켜 독소를 해독 및 배출하고, 자연면역인자인 피부항균펩타이드 hBD3의 발현을 증가시켜 피부를 보호하며, GPX1, 카탈라아제(catalase), Trx1, Prdx1의 항산화 단백질의 발현을 증가시켜 활성산소의 생성을 억제함으로써 피부 보호 및 노화 억제의 효과를 갖는다.
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