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Machine translation
1. (WO2012093738) COMPOSITION FOR COMBATING OXIDATION AND ALLEVIATING DETRIMENTAL EFFECTS ON SKIN CAUSED BY ASIAN DUST
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2012/093738 International Application No.: PCT/KR2011/000010
Publication Date: 12.07.2012 International Filing Date: 03.01.2011
IPC:
A61K 36/58 (2006.01) ,A61K 36/62 (2006.01) ,A61K 8/97 (2006.01) ,A61P 17/00 (2006.01) ,A61P 39/06 (2006.01) ,A61Q 19/00 (2006.01)
Applicants: CHOI, Hyun[KR/KR]; KR (UsOnly)
KIM, Sun Mi[KR/KR]; KR (UsOnly)
MOON, Sung Ho[KR/KR]; KR (UsOnly)
LIM, Hyung Jun[KR/KR]; KR (UsOnly)
KIM, Ji Hyun[KR/KR]; KR (UsOnly)
LEE, Tae Ryong[KR/KR]; KR (UsOnly)
SHIN, Dong Wook[KR/KR]; KR (UsOnly)
KANG, Hak Hee[KR/KR]; KR (UsOnly)
AMOREPACIFIC CORPORATION[KR/KR]; 181 2-ka, Hangang-ro, Yongsan-gu Seoul 140-777, KR (AllExceptUS)
Inventors: CHOI, Hyun; KR
KIM, Sun Mi; KR
MOON, Sung Ho; KR
LIM, Hyung Jun; KR
KIM, Ji Hyun; KR
LEE, Tae Ryong; KR
SHIN, Dong Wook; KR
KANG, Hak Hee; KR
Agent: KIM, Sun-young; Korea Coal Center, 10th Floor 80-6 Susong-dong, Chongro-ku Seoul 110-727, KR
Priority Data:
Title (EN) COMPOSITION FOR COMBATING OXIDATION AND ALLEVIATING DETRIMENTAL EFFECTS ON SKIN CAUSED BY ASIAN DUST
(FR) COMPOSITION POUR COMBATTRE L'OXYDATION ET DIMINUER LES EFFETS CUTANÉS INDÉSIRABLES PROVOQUÉS PAR LA POUSSIÈRE D'ASIE
(KO) 항산화용 및 황사에 의한 피부 유해영향 완화용 조성물
Abstract: front page image
(EN) The present invention relates to a composition for combating oxidation and alleviating the detrimental effects on skin caused by Asian Dust, the composition containing Melia azedarach bark and Nelumbo nucifera leaf extracts as a novel skin irritation alleviating agent. More specifically, the present invention contains Melia azedarach bark and Nelumbo nucifera leaf extracts, and entails: detoxification and expulsion of toxins by increasing the expression of NQO1 which is an enzyme that detoxifies toxins and of GSTT1 which is an enzyme that expels toxins; protection of the skin by increasing the expression of the skin antimicrobial peptide hBD3 which is a natural immune factor; and suppression of the production of active oxygen by increasing expression of the antioxidant proteins GPX1, catalase, Trx1 and Prdx1. Consequently, the invention has the advantages of skin protection and ageing suppression.
(FR) La présente invention concerne une composition pour combattre l'oxydation et pour diminuer les effets cutanés indésirables provoqués par la poussière d'Asie, la composition contenant de l'écorce de Melia azedarach et des extraits de feuilles de Nelumbo nucifera en tant que nouvel agent diminuant l'irritation cutanée. Plus particulièrement, la présente invention contient de l'écorce de Melia azedarach et des extraits de feuilles de Nelumbo nucifera et permet : la détoxication et l'expulsion de toxines par l'augmentation de l'expression de NQO1, qui est une enzyme qui détoxique les toxines, et de GFTT1, qui est une enzyme qui expulse les toxines ; la protection de la peau par l'augmentation de l'expression du peptide hBD3 antimicrobien cutané qui est un facteur immunitaire naturel ; la suppression de la production d'oxygène actif par l'augmentation de l'expression des protéines anti-oxydantes GPX1, catalase, Trx1 et Prdx1. L'invention présente donc les avantages d'une protection cutanée et de l'inhibition du vieillissement.
(KO) 본 발명은 새로운 피부자극 완화제로서 고련피 및 연꽃잎 추출물을 함유하는 항산화용 및 황사에 의한 피부 유해영향 완화용 조성물에 관한 것이다. 구체적으로, 본 발명은 고련피 및 연꽃잎 추출물을 함유하여, 독소를 해독하는 효소인 NQO1, 독소를 배출하는 효소인 GSTT1의 발현을 증가시켜 독소를 해독 및 배출하고, 자연면역인자인 피부항균펩타이드 hBD3의 발현을 증가시켜 피부를 보호하며, GPX1, 카탈라아제(catalase), Trx1, Prdx1의 항산화 단백질의 발현을 증가시켜 활성산소의 생성을 억제함으로써 피부 보호 및 노화 억제의 효과를 갖는다.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: Korean (KO)
Filing Language: Korean (KO)