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1. (WO2012091093) COMPREHENSIVE GLAUCOMA DETERMINATION METHOD UTILIZING GLAUCOMA DIAGNOSIS CHIP AND DEFORMED PROTEOMICS CLUSTER ANALYSIS
Latest bibliographic data on file with the International Bureau   

Pub. No.: WO/2012/091093 International Application No.: PCT/JP2011/080393
Publication Date: 05.07.2012 International Filing Date: 28.12.2011
IPC:
C12M 1/00 (2006.01) ,C12Q 1/68 (2006.01) ,G06N 3/00 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
M
APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY
1
Apparatus for enzymology or microbiology
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
G PHYSICS
06
COMPUTING; CALCULATING; COUNTING
N
COMPUTER SYSTEMS BASED ON SPECIFIC COMPUTATIONAL MODELS
3
Computer systems based on biological models
Applicants: TASHIRO, Kei[JP/JP]; JP
KINOSHITA, Shigeru[JP/JP]; JP
YAGI, Tomohito[JP/JP]; JP (UsOnly)
NAKANO, Masakazu[JP/JP]; JP (UsOnly)
MORI, Kazuhiko[JP/JP]; JP (UsOnly)
IKEDA, Yoko[JP/JP]; JP (UsOnly)
UENO, Morio[JP/JP]; JP (UsOnly)
TOKUDA, Yuichi[JP/JP]; JP (UsOnly)
YAGI, Katsumi[JP/JP]; JP (UsOnly)
YOSHII, Kengo[JP/JP]; JP (UsOnly)
FUWA, Masahiro[JP/JP]; JP (UsOnly)
SANTEN PHARMACEUTICAL CO., LTD.[JP/JP]; 9-19, Shimoshinjo 3-chome, Higashiyodogawa-ku, Osaka-shi, Osaka 5338651, JP (AllExceptUS)
Inventors: TASHIRO, Kei; JP
KINOSHITA, Shigeru; JP
YAGI, Tomohito; JP
NAKANO, Masakazu; JP
MORI, Kazuhiko; JP
IKEDA, Yoko; JP
UENO, Morio; JP
TOKUDA, Yuichi; JP
YAGI, Katsumi; JP
YOSHII, Kengo; JP
FUWA, Masahiro; JP
Agent: SK INTELLECTUAL PROPERTY LAW FIRM; Cerulean Tower 15th Floor 26-1, Sakuragaoka-cho Shibuya-ku, Tokyo 1508512, JP
Priority Data:
2010-29417628.12.2010JP
Title (EN) COMPREHENSIVE GLAUCOMA DETERMINATION METHOD UTILIZING GLAUCOMA DIAGNOSIS CHIP AND DEFORMED PROTEOMICS CLUSTER ANALYSIS
(FR) PROCÉDÉ DE DÉTERMINATION COMPLÈTE DU GLAUCOME À L'AIDE D'UNE PUCE DE DIAGNOSTIC DU GLAUCOME, ET ANALYSE DE GROUPES DE PROTÉOMIQUE DÉFORMÉS
(JA) 緑内障診断チップと変形プロテオミクスクラスター解析による緑内障統合的判定方法
Abstract:
(EN) Provided is a technique for determining a physiological attribute in a mammal, including the onset or progression of human glaucoma, with high accuracy. The results of the determination of genotype date and the results of the determination of cytokine date are consolidated by a consolidated determination unit (114),;comparison is made for determining as to which is larger, the number of Case determination procedures or the number of Control determination procedures (S330); and it is determined as Case (glaucoma) when the number of Case determination procedures is larger and it is determined as Control (normal person) when the number of Control determination procedures is larger.
(FR) L'invention concerne une technique de détermination d'un attribut physiologique chez un mammifère, comprenant l'apparition ou la progression d'un glaucome humain, à une précision élevée. Les résultats de la détermination des données de génotype et les résultats de la détermination des données de cytokine sont renforcés par une unité de détermination consolidée (114) ; une comparaison est effectuée pour déterminer lequel est le plus grand, entre le nombre de procédures de détermination du Cas ou le nombre de procédures de détermination du Témoin (S330) ; et il est déterminé qu'il s'agit d'un Cas (glaucome) lorsque le nombre de procédures de détermination du Cas est supérieur, et il est déterminé qu'il s'agit d'un Témoin (personne normale) lorsque le nombre de procédures de détermination du Témoin est supérieur.
(JA) ヒト緑内障の発症及び進行をはじめとする哺乳動物の生理状態の属性を精度良く判定する技術を提供する。ジェノタイプデータの判定結果及びサイトカインデータの判定結果を統合判定部114で統合して、Case判定回数及びControl判定回数のどちらが大きいかを比較して(S330)、Case判定回数の方が多ければCase(緑内障)であると判定し、Control判定回数の方が多ければControl(健常者)であると判定する。
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Office (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (EPO) (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: Japanese (JA)
Filing Language: Japanese (JA)