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1. (WO2012090225) NOVEL COCRYSTALS / MOLECULAR SALTS OF METFORMIN WITH OLEOYLETHANOLAMIDE AS AN EFFECTIVE ANTI-DIABETIC + ANTI- OBESITY AGENT
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/090225    International Application No.:    PCT/IN2011/000903
Publication Date: 05.07.2012 International Filing Date: 29.12.2011
IPC:
A01N 37/52 (2006.01), A61K 31/155 (2006.01)
Applicants: NUTRACRYST THERAPEUTICS PRIVATE LIMITED [IN/IN]; C-71, Sector -63 Noida 200130 UP (IN) (For All Designated States Except US).
REDDY, Jaggavarapu Satyanarayana [IN/IN]; (IN) (For US Only).
DANDELA, Rambabu [IN/IN]; (IN) (For US Only).
VISWANADHA, Ganesh Saraswatula [IN/IN]; (IN) (For US Only).
NAGALAPALLI, RaviKumar [IN/IN]; (IN) (For US Only).
SOLOMON, Anand Kamalakaran [IN/IN]; (IN) (For US Only).
JAVED, Iqbal [IN/IN]; (IN) (For US Only).
KRUTHIVENTI, Anil Kumar [IN/IN]; (IN) (For US Only)
Inventors: REDDY, Jaggavarapu Satyanarayana; (IN).
DANDELA, Rambabu; (IN).
VISWANADHA, Ganesh Saraswatula; (IN).
NAGALAPALLI, RaviKumar; (IN).
SOLOMON, Anand Kamalakaran; (IN).
JAVED, Iqbal; (IN).
KRUTHIVENTI, Anil Kumar; (IN)
Agent: P. ARUNA SREE; Patent & Trademark Attorney Gopakumar Nair Associates 3rd Floor, 'Shivmangal', Near Big Bazaar, Akurli Road, Kandivali (East), Mumbai 400 101, Maharashtra (IN)
Priority Data:
3159/DEL/2010 29.12.2010 IN
Title (EN) NOVEL COCRYSTALS / MOLECULAR SALTS OF METFORMIN WITH OLEOYLETHANOLAMIDE AS AN EFFECTIVE ANTI-DIABETIC + ANTI- OBESITY AGENT
(FR) NOUVEAUX CO-CRISTAUX/SELS MOLÉCULAIRES DE METFORMINE ET D'OLÉOYLÉTHANOLAMIDE UTILES EN TANT QU'AGENT ANTIDIABÉTIQUE ET ANTIOBÉSITÉ EFFICACE
Abstract: front page image
(EN)The present invention discloses novel synergistic pharmaceutical co-crystals of Metformin or its pharmaceutically acceptable salts and oleoylethanolamide in fixed stoichiometric ratio at lower dosage, with improved residence time thereby increasing the bioavailability and efficacy, as anti- diabetic agent. The invention further discloses a pharmaceutical composition comprising co- crystals of Metformin or its pharmaceutically acceptable salts and oleoylethanolamide with other antidiabetic agents.
(FR)The présente invention concerne de nouveaux co-cristaux de metformine ou de ses sels pharmaceutiquement acceptables et d'oléoyléthanolamide basés sur un rapport stoechiométrique fixé à une posologie inférieure, qui présentent un temps de séjour amélioré ce qui augmente ainsi la biodisponibilité et l'efficacité, en tant qu'agent anti-diabétique. La présente invention concerne également une composition pharmaceutique comprenant des co-cristaux de metformine ou de ses sels pharmaceutiquement acceptables et d'oléoyléthanolamide, ainsi que d'autres agents antidiabétiques.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)