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1. (WO2012088563) VEGFR-2-SPECIFIC FORMS OF VEGF-D AND VEGF-C AND USES THEREOF
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2012/088563 International Application No.: PCT/AU2011/001511
Publication Date: 05.07.2012 International Filing Date: 23.11.2011
IPC:
C07K 14/475 (2006.01) ,A61K 38/18 (2006.01) ,A61K 39/395 (2006.01) ,A61P 7/00 (2006.01) ,A61P 9/10 (2006.01)
C CHEMISTRY; METALLURGY
07
ORGANIC CHEMISTRY
K
PEPTIDES
14
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
435
from animals; from humans
475
Growth factors; Growth regulators
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
38
Medicinal preparations containing peptides
16
Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
17
from animals; from humans
18
Growth factors; Growth regulators
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
39
Medicinal preparations containing antigens or antibodies
395
Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
7
Drugs for disorders of the blood or the extracellular fluid
A HUMAN NECESSITIES
61
MEDICAL OR VETERINARY SCIENCE; HYGIENE
P
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9
Drugs for disorders of the cardiovascular system
10
for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applicants:
VEGENICS PTY LIMITED [AU/AU]; Level 1,10 Wallace Avenue Toorak, Victoria 3142, AU (AllExceptUS)
ALITALO, Kari [FI/FI]; FI (UsOnly)
JELTSCH, Michael [DE/FI]; FI (UsOnly)
LEPPANEN, Veli-Matti [FI/FI]; FI (UsOnly)
AHO, Kukka [RU/FI]; FI (UsOnly)
ANISIMOV, Andrey [RU/FI]; FI (UsOnly)
TVOROGOV, Denis [RU/FI]; FI (UsOnly)
Inventors:
ALITALO, Kari; FI
JELTSCH, Michael; FI
LEPPANEN, Veli-Matti; FI
AHO, Kukka; FI
ANISIMOV, Andrey; FI
TVOROGOV, Denis; FI
Agent:
GRIFFITH HACK; Patent & Trade Mark Attorneys GPO Box 1285 Melbourne, VIC 3001, AU
Priority Data:
61/458,51724.11.2010US
Title (EN) VEGFR-2-SPECIFIC FORMS OF VEGF-D AND VEGF-C AND USES THEREOF
(FR) FORMES SPÉCIFIQUES DU VEGFR-2 DE VEGF-D ET VEGF-C ET UTILISATIONS ASSOCIÉES
Abstract:
(EN) Amino-terminal truncated forms of Vascular Endothelial Growth Factor-D (VEGF-D) and Vascular Endothelial Growth Factor-C (VEGF-C) which bind to and stimulate Vascular Endothelial Growth Factor Receptor-2 (VEGFR-2) but not Vascular Endothelial Growth Factor Receptor-3 (VEGFR-3), and the use of the same in therapeutic applications in which the stimulation of angiogenesis and not lymphangiogenesis is desired.
(FR) L'invention concerne des formes tronquées amino-terminales du facteur de croissance endothélial vasculaire D (VEGF-D) et du facteur de croissance endothélial vasculaire C (VEGF-C) qui se lient au récepteur du facteur de croissance endothélial vasculaire de type 2 (VEGFR-2) et qui stimulent ce dernier mais pas le récepteur du facteur de croissance endothélial vasculaire de type 3 (VEGFR-3), et leur utilisation dans des applications thérapeutiques dans lesquelles la stimulation de l'angiogenèse mais pas de la lymphangiogenèse est désirée.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)