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1. WO2012081271 - NOVEL TEST METHOD FOR RHEUMATOID ARTHRITIS AND KIT FOR RHEUMATOID ARTHRITIS TEST

Publication Number WO/2012/081271
Publication Date 21.06.2012
International Application No. PCT/JP2011/063563
International Filing Date 14.06.2011
IPC
G01N 33/68 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68involving proteins, peptides or amino acids
G01N 33/53 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
G01N 33/564 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
564for pre-existing immune complex or autoimmune disease
CPC
G01N 2333/4703
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
2333Assays involving biological materials from specific organisms or of a specific nature
435from animals; from humans
46from vertebrates
47Assays involving proteins of known structure or function as defined in the subgroups
4701Details
4703Regulators; Modulating activity
G01N 2800/102
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
2800Detection or diagnosis of diseases
10Musculoskeletal or connective tissue disorders
101Diffuse connective tissue disease, e.g. Sjögren, Wegener's granulomatosis
102Arthritis; Rheumatoid arthritis, i.e. inflammation of peripheral joints
G01N 33/564
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
48Biological material, e.g. blood, urine
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
564for pre-existing immune complex or autoimmune disease ; , i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
Applicants
  • 株式会社ケイティーバイオ KayteeBio, Co.&Ltd. [JP]/[JP] (AllExceptUS)
  • 津坂 憲政 TSUZAKA, Kensei [JP]/[JP] (UsOnly)
Inventors
  • 津坂 憲政 TSUZAKA, Kensei
Agents
  • 正林 真之 SHOBAYASHI, Masayuki
Priority Data
2010-27900515.12.2010JP
Publication Language Japanese (JA)
Filing Language Japanese (JA)
Designated States
Title
(EN) NOVEL TEST METHOD FOR RHEUMATOID ARTHRITIS AND KIT FOR RHEUMATOID ARTHRITIS TEST
(FR) NOUVEAU PROCÉDÉ D'ESSAI POUR L'ARTHRITE RHUMATOÏDE ET TROUSSE POUR ESSAI DE L'ARTHRITE RHUMATOÏDE
(JA) 関節リウマチの検査方法及び関節リウマチ検査用キット
Abstract
(EN)
Provided are: a novel test method for rheumatoid arthritis; and a kit for rheumatoid arthritis test, which is used in the novel test method for rheumatoid arthritis. A test method for rheumatoid arthritis according to the present invention is characterized by comprising a step for measuring the amount of talin in the plasma or serum of an animal subject. This measurement is carried out, for example, by an immunological method using an antibody which binds to talin. A kit for rheumatoid arthritis test according to the present invention is used for such a test method and contains, for example, a solid-phase carrier to which an antibody that binds to talin is affixed.
(FR)
L'invention porte sur un nouveau procédé d'essai pour l'arthrite rhumatoïde ; et sur une trousse pour essai de l'arthrite rhumatoïde, qui est utilisée dans le nouveau procédé d'essai pour l'arthrite rhumatoïde. Un procédé d'essai pour l'arthrite rhumatoïde selon la présente invention est caractérisé en ce qu'il comprend une étape consistant à mesurer la quantité de taline dans le plasma ou le sérum d'un sujet animal. Cette mesure est réalisée, par exemple, par un procédé immunologique utilisant un anticorps qui se lie à la taline. Une trousse pour essai de l'arthrite rhumatoïde selon la présente invention est utilisée pour un tel procédé d'essai et contient, par exemple, un support de phase solide auquel un anticorps qui se lie à la taline est fixé.
(JA)
 新規な関節リウマチの検査方法、及びそのような検査方法に使用される関節リウマチ検査用キットを提供する。 本発明に係る関節リウマチの検査方法は、被検動物の血漿中又は血清中におけるタリン量を測定する工程を含むことを特徴とする。この測定は、例えば、タリンに結合する抗体を用いた免疫学的手法により行われる。本発明に係る関節リウマチ検査用キットは、このような検査方法に使用するためのものであり、例えば、タリンに結合する抗体を固着させた固相担体を含む。
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