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1. WO2012067577 - APATITE FORMING BIOMATERIAL

Publication Number WO/2012/067577
Publication Date 24.05.2012
International Application No. PCT/SE2011/051378
International Filing Date 16.11.2011
IPC
A61K 6/033 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
6Preparations for dentistry
02Use of preparations for artificial teeth, for filling or for capping teeth
027Use of non-metallic elements or compounds thereof, e.g. carbon
033Phosphorus compounds, e.g. apatite
A61K 6/027 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
6Preparations for dentistry
02Use of preparations for artificial teeth, for filling or for capping teeth
027Use of non-metallic elements or compounds thereof, e.g. carbon
A61K 6/06 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
6Preparations for dentistry
02Use of preparations for artificial teeth, for filling or for capping teeth
06Use of inorganic cements
C04B 28/02 2006.01
CCHEMISTRY; METALLURGY
04CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
BLIME; MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
28Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements
02containing hydraulic cements other than calcium sulfates
C04B 28/06 2006.01
CCHEMISTRY; METALLURGY
04CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
BLIME; MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
28Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements
02containing hydraulic cements other than calcium sulfates
06Aluminous cements
C04B 28/18 2006.01
CCHEMISTRY; METALLURGY
04CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
BLIME; MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
28Compositions of mortars, concrete or artificial stone, containing inorganic binders or the reaction product of an inorganic and an organic binder, e.g. polycarboxylate cements
18containing mixtures of the silica-lime type
CPC
A61K 6/838
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
6Preparations for dentistry
80Preparations for artificial teeth, for filling teeth or for capping teeth
831comprising non-metallic elements or compounds thereof, e.g. carbon
838Phosphorus compounds, e.g. apatite
A61K 6/862
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
6Preparations for dentistry
80Preparations for artificial teeth, for filling teeth or for capping teeth
849comprising inorganic cements
862Ca-Al-sulfate-cements
A61K 6/864
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
6Preparations for dentistry
80Preparations for artificial teeth, for filling teeth or for capping teeth
849comprising inorganic cements
864Phosphate cements
A61L 24/001
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
24Surgical adhesives or cements; Adhesives for colostomy devices
001Use of materials characterised by their function or physical properties
A61L 24/02
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICAL ARTICLES
24Surgical adhesives or cements; Adhesives for colostomy devices
02containing inorganic materials
C04B 2111/00836
CCHEMISTRY; METALLURGY
04CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
BLIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE
2111Mortars, concrete or artificial stone or mixtures to prepare them, characterised by specific function, property or use
00474Uses not provided for elsewhere in C04B2111/00
00836for medical or dental applications
Applicants
  • DOXA AB [SE]/[SE] (AllExceptUS)
  • HERMANSSON, Leif [SE]/[SE] (UsOnly)
  • ALPSTEN, Fredrik [SE]/[SE] (UsOnly)
Inventors
  • HERMANSSON, Leif
  • ALPSTEN, Fredrik
Agents
  • BRANN AB
Priority Data
61/414,27616.11.2010US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) APATITE FORMING BIOMATERIAL
(FR) BIOMATÉRIAU DE FORMATION D'APATITE
Abstract
(EN)
The present invention relates to chemically bonded ceramic biomaterials, especially a dental material or an implant material. The main binder system forms a chemically bonded ceramic upon hydration thereof, and comprises powdered calcium aluminate and/or calcium silicate, and phase(s) to secure apatite formation at a pH close to neutrality. A second binder system -a cross-linking organic binder system which provides for initial crosslinking of the freshly mixed paste is advantageously added. The invention relates to a powdered composition for preparing the inventive chemically bonded ceramic biomaterial, and a paste from which the biomaterial is formed, as well as a kit comprising the powdered composition and hydration liquid, as well as methods and use of the biomaterial in dental and implant applications with the aim of remineralisation, integration and bone repair.
(FR)
La présente invention porte sur des biomatériaux céramiques liés chimiquement, en particulier un matériau dentaire ou un matériau d'implant. Le système de liant principal forme une céramique liée chimiquement lors de son hydratation, et comprend de l'aluminate de calcium pulvérulent et/ou du silicate de calcium pulvérulent, et une ou des phases pour fixer une formation d'apatite à un pH proche de la neutralité. Un second système de liant - un système de liant organique de réticulation qui assure une réticulation initiale de la pâte fraichement mélangée - est ajouté avantageusement. L'invention porte sur une composition pulvérulente pour préparer le biomatériau céramique lié chimiquement de l'invention, et sur une pâte à partir de laquelle le biomatériau est formé, ainsi que sur une trousse comprenant la composition pulvérulente et un liquide d'hydratation, ainsi que sur des procédés et l'utilisation du biomatériau dans des applications dentaires et d'implant, en vue d'une reminéralisation, d'une intégration et d'une réparation osseuse.
Also published as
Latest bibliographic data on file with the International Bureau