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1. WO2012066536 - TRANSCRIPTOME SIGNATURES CLASSIFYING ETANERCEPT-TREATED RHEUMATOID ARTHRITIS PATIENTS AS RESPONSIVE OR REFRACTORY

Publication Number WO/2012/066536
Publication Date 24.05.2012
International Application No. PCT/IL2011/000878
International Filing Date 15.11.2011
IPC
C12Q 1/68 2006.01
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
68involving nucleic acids
CPC
C12Q 1/6883
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
68involving nucleic acids
6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
6883for diseases caused by alterations of genetic material
C12Q 2600/158
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
2600Oligonucleotides characterized by their use
158Expression markers
Applicants
  • PREDIGUARD [FR]/[FR] (AllExceptUS)
  • BENECH, Philippe [IL]/[FR] (UsOnly)
Inventors
  • BENECH, Philippe
Agents
  • LUZZATTO & LUZZATTO
Priority Data
61/414,05316.11.2010US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) TRANSCRIPTOME SIGNATURES CLASSIFYING ETANERCEPT-TREATED RHEUMATOID ARTHRITIS PATIENTS AS RESPONSIVE OR REFRACTORY
(FR) SIGNATURES DE TRANSCRIPTOME PERMETTANT DE DISCRIMINER DES PATIENTS ATTEINTS D'UNE POLYARTHRITE RHUMATOÏDE (RA) TRAITÉS PAR L'ÉTANERCEPT SELON LEUR SENSIBILITÉ OU ÉTAT DE RÉSISTANCE
Abstract
(EN)
A method for determining whether an etanercept- or anti-TNF-treated rheumatoid arthritis (RA) patient is an etanercept/anti-TNF responder (R) or an etanercept/anti-TNF non-responder (NR).
(FR)
L'invention concerne un procédé de détermination de savoir si un patient atteint d'une polyarthrite rhumatoïde (RA) traité par l'étanercept ou un anti-TNF est sensible à l'étanercept/anti-TNF (R) ou non sensible (NR) à l'étanercept/anti-TNF.
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