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1. WO2012066485 - AGAVE FRUCTANS COMPOSITIONS AND THEIR USE IN MINERAL ABSORPTION

Publication Number WO/2012/066485
Publication Date 24.05.2012
International Application No. PCT/IB2011/055113
International Filing Date 16.11.2011
IPC
A61K 31/70 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
A61K 31/702 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
702Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
A61K 31/715 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
A61P 19/10 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19Drugs for skeletal disorders
08for bone diseases, e.g. rachitism, Paget's disease
10for osteoporosis
A61P 19/08 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19Drugs for skeletal disorders
08for bone diseases, e.g. rachitism, Paget's disease
CPC
A61K 31/70
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
A61K 31/702
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
702Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
A61K 31/715
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
A61P 19/08
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19Drugs for skeletal disorders
08for bone diseases, e.g. rachitism, Paget's disease
A61P 19/10
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
19Drugs for skeletal disorders
08for bone diseases, e.g. rachitism, Paget's disease
10for osteoporosis
Applicants
  • CENTRO DE INVESTIGACIÓN Y DE ESTUDIOS AVANZADOS DEL INSTITUTO POLITÉCNICO NACIONAL [MX]/[MX] (AllExceptUS)
  • LÓPEZ PÉREZ, Mercedes, Guadalupe [MX]/[MX] (UsOnly)
  • GARCÍA VIEYRA, María, Isabel [MX]/[MX] (UsOnly)
Inventors
  • LÓPEZ PÉREZ, Mercedes, Guadalupe
  • GARCÍA VIEYRA, María, Isabel
Agents
  • CARREÑO SÁNCHEZ, Luis Antonio
Priority Data
MX/a/2010/001260519.11.2010MX
MX/a/2011/00752914.07.2011MX
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) AGAVE FRUCTANS COMPOSITIONS AND THEIR USE IN MINERAL ABSORPTION
(FR) COMPOSITIONS DE FRUCTANES D'AGAVE ET LEUR UTILISATION POUR L'ABSORPTION DES MINÉRAUX
Abstract
(EN)
The present invention relates to compositions comprising Agave fructans to stimulate the absorption of mineral salts and the fixation of bone in mammals, under osteoporosis condition, resulting in pronounced beneficial effects also in lowering plasma glucose levels and body weight reduction measured in ovariectomized mice, administering a standard diet and the compositions of the invention. The Agave fructans compositions of the invention have effects that outweigh inulin-type fructans known from other species, attributable mainly to the branched and non-linear structure of Agave fructans, as is the case with inulin.
(FR)
Cette invention concerne des compositions comprenant des fructanes d'agave pour stimuler l'absorption des sels minéraux et la fixation de l'os chez les mammifères souffrant d'ostéoporose, qui permettent d'obtenir des effets bénéfiques prononcés également en termes d'abaissement des taux glycémiques plasmatiques et de réduction du poids corporel, mesurés chez des souris ovariectomisées par administration d'un régime standard et des compositions selon l'invention. Les compositions de fructanes d'agave selon l'invention ont des effets qui dépassent ceux des fructanes de type inuline connus provenant d'autres espèces, principalement imputables à la structure ramifiée et non linéaire des fructanes d'agave, comme dans le cas de l'inuline.
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