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1. WO2012065176 - CITRULLINATED PROTEINS: A POST-TRANSLATED MODIFICATION OF MYOCARDIAL PROTEINS AS MARKER OF PHYSIOLOGICAL AND PATHOLOGICAL DISEASE

Publication Number WO/2012/065176
Publication Date 18.05.2012
International Application No. PCT/US2011/060640
International Filing Date 14.11.2011
IPC
G01N 33/68 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
68involving proteins, peptides or amino acids
G01N 33/53 2006.01
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
33Investigating or analysing materials by specific methods not covered by groups G01N1/-G01N31/131
48Biological material, e.g. blood, urine; Haemocytometers
50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
53Immunoassay; Biospecific binding assay; Materials therefor
CPC
A61P 43/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
43Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
A61P 9/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
9Drugs for disorders of the cardiovascular system
C12Q 1/34
CCHEMISTRY; METALLURGY
12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS
1Measuring or testing processes involving enzymes, nucleic acids or microorganisms
34involving hydrolase
G01N 2440/18
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
2440Post-translational modifications [PTMs] in chemical analysis of biological material
18citrullination
G01N 2800/32
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
2800Detection or diagnosis of diseases
32Cardiovascular disorders
G01N 2800/50
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
2800Detection or diagnosis of diseases
50Determining the risk of developing a disease
Applicants
  • THE JOHNS HOPKINS UNIVERSITY [US]/[US] (AllExceptUS)
  • FERT-BOBER, Justyna P. [PL]/[US] (UsOnly)
  • VAN EYK, Jennifer E. [CA]/[US] (UsOnly)
Inventors
  • FERT-BOBER, Justyna P.
  • VAN EYK, Jennifer E.
Agents
  • DALEY, Henry J.
Priority Data
61/412,81912.11.2010US
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) CITRULLINATED PROTEINS: A POST-TRANSLATED MODIFICATION OF MYOCARDIAL PROTEINS AS MARKER OF PHYSIOLOGICAL AND PATHOLOGICAL DISEASE
(FR) PROTÉINES CITRULLINÉES:MODIFICATION POST-TRADUCTION DE PROTÉINES MYOCARDIQUES COMME MARQUEUR DE MALADIE PHYSIOLOGIQUE ET PATHOLOGIQUE
Abstract
(EN)
Disclosed herein are methods for diagnosing cardiovascular disease. The methods comprise detection of citrullinated proteins.
(FR)
La présente invention concerne des méthodes de diagnostic de maladies cardiovasculaires. Les méthodes comportent la détection de protéines citrullinées.
Latest bibliographic data on file with the International Bureau