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1. WO2012059723 - SCANNING METHODS AND APPARATUS

Publication Number WO/2012/059723
Publication Date 10.05.2012
International Application No. PCT/GB2011/001559
International Filing Date 04.11.2011
IPC
A61B 5/00 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Measuring for diagnostic purposes; Identification of persons
CPC
A61B 5/0066
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Detecting, measuring or recording for diagnostic purposes
0059using light, e.g. diagnosis by transillumination, diascopy, fluorescence
0062Arrangements for scanning
0066Optical coherence imaging
A61B 5/445
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Detecting, measuring or recording for diagnostic purposes
44Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
441Skin evaluation, e.g. for skin disorder diagnosis
445Evaluating skin irritation or skin trauma, e.g. rash, eczema, wound, bed sore
A61B 5/4552
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
BDIAGNOSIS; SURGERY; IDENTIFICATION
5Detecting, measuring or recording for diagnostic purposes
45For evaluating or diagnosing the musculoskeletal system or teeth
4538Evaluating a particular part of the muscoloskeletal system or a particular medical condition
4542Evaluating the mouth, e.g. the jaw
4552Evaluating soft tissue within the mouth, e.g. gums or tongue
G01N 21/17
GPHYSICS
01MEASURING; TESTING
NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
21Investigating or analysing materials by the use of optical means, i.e. using infra-red, visible or ultra-violet light
17Systems in which incident light is modified in accordance with the properties of the material investigated
Applicants
  • QUEEN MARY & WESTFIELD COLLEGE [GB]/[GB] (AllExceptUS)
  • SECRETARY OF STATE FOR BUSINESS, INNOVATION & SKILLS [GB]/[GB] (AllExceptUS)
  • TOMLINS, Peter (UsOnly)
  • ADEGUN, Oluyori Kutulola (UsOnly)
  • FORTUNE, Farida (UsOnly)
Inventors
  • TOMLINS, Peter
  • ADEGUN, Oluyori Kutulola
  • FORTUNE, Farida
Agents
  • DOWNING, Michael Philip
Priority Data
1018743.305.11.2010GB
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) SCANNING METHODS AND APPARATUS
(FR) PROCÉDÉS ET APPAREIL DE BALAYAGE
Abstract
(EN)
There is provided a method of identifying a region of interest in sample. The method comprises obtaining one or more optical coherence tomography (OCT) axial scans at one or more locations over the sample surface; for each axial scan, determining an integrated total of OCT intensity over the depth of the scan, and determining an attenuation depth into the sample at which a predetermined fraction of the integrated total is reached; and determining from the one or more attenuation depths a region of interest in the sample. Generally, the method does not rely the accuracy (or inaccuracy) of any particular scientific model of scattering and attenuation. It is therefore robust and can be employed across a wide variety of samples, including non -biological ones.
(FR)
L'invention porte sur un procédé d'identification d'une région d'intérêt dans un échantillon. Le procédé comprend l'obtention d'un ou plusieurs balayages axiaux de tomographie par cohérence optique (OCT) à un ou plusieurs emplacements sur la surface d'échantillon; pour chaque balayage axial, la détermination d'un total intégré d'intensité de tomographie par cohérence optique (OCT) sur la profondeur de balayage, et la détermination d'une profondeur d'atténuation dans l'échantillon à laquelle une fraction prédéterminée du total intégré est atteinte; et la détermination, à partir de la ou des profondeurs d'atténuation, d'une région d'intérêt dans l'échantillon. D'une manière générale, le procédé ne repose pas sur la précision (ou le manque de précision) d'un quelconque modèle scientifique particulier de diffusion et d'atténuation. Il est donc robuste et peut être employé à travers une grande diversité d'échantillons, comprenant des échantillons non biologiques.
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