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1. WO2012056369 - MULTILAYER MICROFLUIDIC PROBE HEAD WITH IMMERSION CHANNELS AND FABRICATION THEREOF

Publication Number WO/2012/056369
Publication Date 03.05.2012
International Application No. PCT/IB2011/054614
International Filing Date 18.10.2011
IPC
B01J 19/00 2006.01
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
19Chemical, physical or physico-chemical processes in general; Their relevant apparatus
B01L 3/00 2006.01
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
CPC
B01L 2200/0636
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2200Solutions for specific problems relating to chemical or physical laboratory apparatus
06Fluid handling related problems
0636Focussing flows, e.g. to laminate flows
B01L 2200/0673
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2200Solutions for specific problems relating to chemical or physical laboratory apparatus
06Fluid handling related problems
0673Handling of plugs of fluid surrounded by immiscible fluid
B01L 2200/0694
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2200Solutions for specific problems relating to chemical or physical laboratory apparatus
06Fluid handling related problems
0694Creating chemical gradients in a fluid
B01L 2200/12
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2200Solutions for specific problems relating to chemical or physical laboratory apparatus
12Specific details about manufacturing devices
B01L 2300/0887
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
2300Additional constructional details
08Geometry, shape and general structure
0887Laminated structure
B01L 3/502707
BPERFORMING OPERATIONS; TRANSPORTING
01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
3Containers or dishes for laboratory use, e.g. laboratory glassware
50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
502with fluid transport, e.g. in multi-compartment structures
5027by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
502707characterised by the manufacture of the container or its components
Applicants
  • INTERNATIONAL BUSINESS MACHINES CORPORATION [US]/[US] (AllExceptUS)
  • DELAMARCHE, Emmanuel [FR]/[CH] (UsOnly)
  • KAIGALA, Govind [CA]/[CH] (UsOnly)
  • LOVCHIK, Robert [CH]/[CH] (UsOnly)
Inventors
  • DELAMARCHE, Emmanuel
  • KAIGALA, Govind
  • LOVCHIK, Robert
Agents
  • RAGOT, Sébastien
Priority Data
10189469.929.10.2010EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) MULTILAYER MICROFLUIDIC PROBE HEAD WITH IMMERSION CHANNELS AND FABRICATION THEREOF
(FR) TÊTE DE SONDE MICROFLUIDIQUE MULTICOUCHE PRÉSENTANT DES CANAUX D'IMMERSION ET SON FABRICATION
Abstract
(EN)
The invention is directed to a microfluidic probe head (100) with a base layer (120) comprising: at least two processing liquid microchannel (123, 124) in fluid communication with a processing liquid aperture (121, 122) on a face of the base 10 layer; and an immersion liquid microchannel (223, 224) in fluid communication with a immersion liquid aperture (221, 222) on a face of the base layer, wherein the microfluidic probe head is configured to allow, in operation, processing liquid provided through the processing liquid aperture to merge into immersion liquid provided through the immersion liquid aperture. An additional layer can be provided 15 to close the microchannels. Such a multilayered head is compact and easier to fabricate than heads made with unitary construction. The head can further be interfaced with tubing using e.g. a standard fitting for tubing port.
(FR)
L'invention porte sur une tête de sonde microfluidique (100) comportant une couche de base (120), laquelle tête comprend : au moins deux microcanaux de liquide de traitement (123, 124) en communication fluidique avec une ouverture de liquide de traitement (121, 122) sur une face de la couche de base; et un microcanal de liquide d'immersion (223, 224) en communication fluidique avec une ouverture de liquide d'immersion (221, 222) sur une face de la couche de base, la tête de sonde microfluidique étant configurée de façon à permettre, lors du fonctionnement, à un liquide de traitement fourni à travers l'ouverture de liquide de traitement de se mélanger dans un liquide d'immersion disposé à travers l'ouverture de liquide d'immersion. Une couche additionnelle peut être disposée de façon à fermer les microcanaux. Une telle tête multicouche est compacte et plus facile à fabriquer que des têtes réalisées avec une construction unitaire. La tête peut de plus venir en interface avec un tuyau, par exemple à l'aide d'un raccord standard pour orifice de tuyau.
Also published as
DE112011103579
GB1308835.6
Latest bibliographic data on file with the International Bureau