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1. WO2012055844 - SEMULOPARIN FOR USE AS AN ANTITHROMBOTIC TREATMENT IN MAJOR ABDOMINAL SURGERY WITH IMPROVED SAFETY IN TERMS OF CLINICALLY RELEVANT BLEEDINGS AND MAJOR BLEEDINGS

Publication Number WO/2012/055844
Publication Date 03.05.2012
International Application No. PCT/EP2011/068600
International Filing Date 25.10.2011
IPC
A61K 31/727 2006.01
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
726Glycosaminoglycans, i.e. mucopolysaccharides
727Heparin; Heparan
CPC
A61K 31/727
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
70Carbohydrates; Sugars; Derivatives thereof
715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
726Glycosaminoglycans, i.e. mucopolysaccharides
727Heparin; Heparan
A61K 9/0019
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
0012Galenical forms characterised by the site of application
0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Applicants
  • AVENTIS PHARMA S.A. [FR]/[FR] (AllExceptUS)
  • DESTREE, Dominique [FR]/[FR] (UsOnly)
  • LAWSON, Fransesca [US]/[US] (UsOnly)
  • MURPHY, Judith [US]/[US] (UsOnly)
Inventors
  • DESTREE, Dominique
  • LAWSON, Fransesca
  • MURPHY, Judith
Agents
  • ROMANOWSKI, Caroline
Priority Data
10306184.228.10.2010EP
Publication Language English (EN)
Filing Language English (EN)
Designated States
Title
(EN) SEMULOPARIN FOR USE AS AN ANTITHROMBOTIC TREATMENT IN MAJOR ABDOMINAL SURGERY WITH IMPROVED SAFETY IN TERMS OF CLINICALLY RELEVANT BLEEDINGS AND MAJOR BLEEDINGS
(FR) SÉMLUPARINE DESTINÉE À ÊTRE UTILISÉE EN TANT QUE TRAITEMENT ANTITHROMBOTIQUE DANS UNE CHIRURGIE ABDOMINALE MAJEURE AYANT UNE SÉCURITÉ AMÉLIORÉE EN TERMES DE SAIGNEMENTS CLINIQUEMENT PERTINENTS ET DE SAIGNEMENTS MAJEURS
Abstract
(EN)
The invention relates to the use of semuloparin or a pharmaceutically acceptable salt thereof as an antithrombotic treatment in patients undergoing major abdominal surgery, wherein said use involves an improved safety in terms of clinically relevant bleedings and of major bleedings compared to a standard antithrombotic treatment.
(FR)
L'invention porte sur l'utilisation de sémuloparine ou d'un sel pharmaceutiquement acceptable de celle-ci en tant que traitement antithrombotique chez des patients subissant une chirurgie abdominale majeure, ladite utilisation mettant en jeu une sécurité améliorée en termes de saignements cliniquement pertinents et de saignements majeurs par comparaison avec un traitement antithrombotique standard.
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