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1. (WO2012054738) COMBINATION OF AN AMINOACYL - TRNA SYNTHETASE INHIBITOR WITH A FURTHER ANTIBACTERIAL AGENT FOR ATTENUATING MULTIPLE DRUG RESISTANCE
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/054738    International Application No.:    PCT/US2011/057119
Publication Date: 26.04.2012 International Filing Date: 20.10.2011
IPC:
A61K 31/165 (2006.01), A61K 31/351 (2006.01), A61K 31/407 (2006.01), A61K 31/422 (2006.01), A61K 31/43 (2006.01), A61K 31/7048 (2006.01), A61K 31/7056 (2006.01), A61K 45/06 (2006.01), A61P 31/04 (2006.01)
Applicants: BROWN UNIVERSITY [US/US]; One Prospect Street Providence, RI 02912 (US) (For All Designated States Except US).
SELLO, Jason, K. [US/US]; (US) (For US Only).
VECCHIONE, James, J. [US/US]; (US) (For US Only)
Inventors: SELLO, Jason, K.; (US).
VECCHIONE, James, J.; (US)
Agent: MURRAY, Mary, K.; Hamilton, Brook, Smith & Reynolds, P.C. 530 Virginia Road P.O. Box 9133 Concord, MA 01742-9133 (US)
Priority Data:
61/405,771 22.10.2010 US
61/426,289 22.12.2010 US
Title (EN) COMBINATION OF AN AMINOACYL - TRNA SYNTHETASE INHIBITOR WITH A FURTHER ANTIBACTERIAL AGENT FOR ATTENUATING MULTIPLE DRUG RESISTANCE
(FR) ASSOCIATION D'UN INHIBITEUR DE L'AMINOACYL-ARNT SYNTHÉTASE ET D'UN AUTRE AGENT ANTIBACTÉRIEN POUR L'ATTÉNUATION D'UNE MULTIRÉSISTANCE MÉDICAMENTEUSE
Abstract: front page image
(EN)Bacterial multidrug resistance is attenuated in a subject by administering an aminoacyl-tRNA synthetase inhibitor and an antibacterial agent to the subject, wherein the aminoacyl-tRNA synthetase inhibitor is distinct from the antibacterial agent.
(FR)Il est possible d'atténuer une multirésistance médicamenteuse bactérienne chez un sujet par l'administration d'un inhibiteur de l'aminoacyl-ARNt synthétase et d'un agent antibactérien au sujet, l'inhibiteur de l'aminoacyl-ARNt synthétase étant distinct de l'agent antibactérien.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)