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1. (WO2012054735) SYSTEMS AND METHODS FOR ASSESSING BIOMOLECULE CHARACTERISTICS
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/054735    International Application No.:    PCT/US2011/057115
Publication Date: 26.04.2012 International Filing Date: 20.10.2011
IPC:
C12Q 1/68 (2006.01)
Applicants: BIONANO GENOMICS, INC. [US/US]; 3701 Market Street, 4th Floor Philadelphia, PA 19104 (US) (For All Designated States Except US).
DESHPANDE, Parikshit, A. [CA/US]; (US) (For US Only).
MARLIN, Arthur, G. [US/US]; (US) (For US Only).
KOCHERSPERGER, Michael [US/US]; (US) (For US Only).
SHARONOV, Alexey [RU/US]; (US) (For US Only).
STEDMAN, William [US/US]; (US) (For US Only).
XIAO, Ming [US/US]; (US) (For US Only).
SADOWSKI, Henry, B. [US/US]; (US) (For US Only).
DAS, Someskumar [IN/US]; (US) (For US Only).
AKANA, Matthew [US/US]; (US) (For US Only).
BOZINOV, Daniel [DE/US]; (US) (For US Only).
REQUA, Michael [US/US]; (US) (For US Only).
CAO, Han [CN/US]; (US) (For US Only)
Inventors: DESHPANDE, Parikshit, A.; (US).
MARLIN, Arthur, G.; (US).
KOCHERSPERGER, Michael; (US).
SHARONOV, Alexey; (US).
STEDMAN, William; (US).
XIAO, Ming; (US).
SADOWSKI, Henry, B.; (US).
DAS, Someskumar; (US).
AKANA, Matthew; (US).
BOZINOV, Daniel; (US).
REQUA, Michael; (US).
CAO, Han; (US)
Agent: CALDWELL, John, W.; Woodcock Washburn LLP Cira Centre, 12th Floor 2929 Arch Street Philadelphia, PA 19104 (US)
Priority Data:
61/407,302 27.10.2010 US
61/418,516 01.12.2010 US
61/394,915 20.10.2010 US
61/407,182 27.10.2010 US
Title (EN) SYSTEMS AND METHODS FOR ASSESSING BIOMOLECULE CHARACTERISTICS
(FR) SYSTÈMES ET PROCÉDÉS POUR ÉVALUER DES CARACTÉRISTIQUES DE BIOMOLÉCULES
Abstract: front page image
(EN)Provided are methods and systems for assessing the presence and extent of damage on a polynucleotide. The methods include incorporating a label at the site of the damage and imaging the label to determine the presence and extent of the damage. The systems include devices capable of performing damage assessment on single molecules.
(FR)L'invention concerne des procédés et des systèmes pour évaluer la présence et l'étendue de dommage sur un polynucléotide. Les procédés consistent à incorporer une étiquette au niveau du site du dommage et à réaliser l'imagerie de l'étiquette pour déterminer la présence et l'étendue du dommage. Les systèmes comprennent des dispositifs permettant d'effectuer une évaluation de dommage sur des molécules uniques.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)