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1. (WO2012054510) OXADIAZOLE COMPOUNDS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/054510    International Application No.:    PCT/US2011/056747
Publication Date: 26.04.2012 International Filing Date: 18.10.2011
IPC:
C07D 417/14 (2006.01), A61K 31/427 (2006.01), C07D 413/12 (2006.01), A61K 31/422 (2006.01), A61K 31/4439 (2006.01), C07D 413/14 (2006.01), A61K 31/4245 (2006.01), A61P 25/28 (2006.01)
Applicants: COMENTIS, INC. [US/US]; 280 Utah Avenue, Suite 275 South San Francisco, CA 94080 (US) (For All Designated States Except US).
ASTELLAS PHARMA INC. [JP/JP]; 2-3-11 Nihonbashi-Honcho, Chuo-ku Tokyo, 103-8411 (JP) (For All Designated States Except US).
BILCER, Geoffrey, M. [US/US]; (US) (For US Only).
DEVASAMUDRAM, Thippeswamy [IN/US]; (US) (For US Only).
LILLY, John, C. [US/US]; (US) (For US Only).
ANKALA, Sudha, V. [IN/US]; (US) (For US Only).
MOSKALEV, Nikolai, V. [RU/US]; (US) (For US Only).
LIU, Chunfeng [CN/US]; (US) (For US Only).
INOUE, Makoto [JP/JP]; (JP) (For US Only).
KAWAKAMI, Shimpei [JP/JP]; (JP) (For US Only).
MUNAKATA, Ryosuke [JP/JP]; (JP) (For US Only).
HAMAJIMA, Toshihiro [JP/JP]; (JP) (For US Only)
Inventors: BILCER, Geoffrey, M.; (US).
DEVASAMUDRAM, Thippeswamy; (US).
LILLY, John, C.; (US).
ANKALA, Sudha, V.; (US).
MOSKALEV, Nikolai, V.; (US).
LIU, Chunfeng; (US).
INOUE, Makoto; (JP).
KAWAKAMI, Shimpei; (JP).
MUNAKATA, Ryosuke; (JP).
HAMAJIMA, Toshihiro; (JP)
Agent: TIAN, Zong-Qiang, Bill; Morrison & Foerster LLP 755 Page Mill Road Palo Alto, CA 94304-1018 (US)
Priority Data:
61/394,680 19.10.2010 US
Title (EN) OXADIAZOLE COMPOUNDS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF
(FR) COMPOSÉS OXADIAZOLE QUI INHIBENT L'ACTIVITÉ DE LA BÊTA-SECRÉTASE, ET LEURS PROCÉDÉS D'UTILISATION
Abstract: front page image
(EN)The invention provides novel beta-secretase inhibitors and methods for their including methods of treating Alzheimer's disease.
(FR)L'invention concerne de nouveaux inhibiteurs de bêta-secrétase et des procédés pour leur utilisation, notamment des méthodes de traitement de la maladie d'Alzheimer.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)