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1. WO2012054090 - METHODS OF INCREASING SOLUBILITY OF POORLY SOLUBLE COMPOUNDS AND METHODS OF MAKING AND USING FORMULATIONS OF SUCH COMPOUNDS

Publication Number WO/2012/054090
Publication Date 26.04.2012
International Application No. PCT/US2011/001802
International Filing Date 24.10.2011
IPC
A61K 9/70 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
70Web, sheet or filament bases
A61K 9/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
9Medicinal preparations characterised by special physical form
A61K 31/00 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
A61Q 17/04 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
QSPECIFIC USE OF COSMETICS OR SIMILAR TOILET PREPARATIONS
17Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
04Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
A61K 8/49 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
8Cosmetics or similar toilet preparations
18characterised by the composition
30containing organic compounds
49containing heterocyclic compounds
A61K 31/353 2006.1
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
35having six-membered rings with one oxygen as the only ring hetero atom
352condensed with carbocyclic rings, e.g. cannabinols, methantheline
3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
CPC
A61K 2800/412
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
2800Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
40Chemical, physico-chemical or functional or structural properties of particular ingredients
41Particular ingredients further characterized by their size
412Microsized, i.e. having sizes between 0.1 and 100 microns
A61K 2800/592
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
2800Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
40Chemical, physico-chemical or functional or structural properties of particular ingredients
59Mixtures
592Mixtures of compounds complementing their respective functions
A61K 2800/652
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
2800Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
40Chemical, physico-chemical or functional or structural properties of particular ingredients
60Particulates further characterized by their structure or composition
65Characterized by the composition of the particulate/core
652The particulate/core comprising organic material
A61K 31/00
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
A61K 31/05
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
05Phenols
A61K 31/353
AHUMAN NECESSITIES
61MEDICAL OR VETERINARY SCIENCE; HYGIENE
KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
31Medicinal preparations containing organic active ingredients
33Heterocyclic compounds
335having oxygen as the only ring hetero atom, e.g. fungichromin
35having six-membered rings with one oxygen as the only ring hetero atom
352condensed with carbocyclic rings, e.g. cannabinols, methantheline
3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
Applicants
  • API GENESIS, LLC [US]/[US] (AllExceptUS)
  • BIRBARA, Philip, J. [US]/[US] (UsOnly)
Inventors
  • BIRBARA, Philip, J.
Agents
  • WILSON, Mary, J.
Priority Data
13/064,88222.04.2011US
PCT/US2010/00282122.10.2010US
Publication Language English (en)
Filing Language English (EN)
Designated States
Title
(EN) METHODS OF INCREASING SOLUBILITY OF POORLY SOLUBLE COMPOUNDS AND METHODS OF MAKING AND USING FORMULATIONS OF SUCH COMPOUNDS
(FR) PROCÉDÉS VISANT À ACCROÎTRE LA SOLUBILITÉ DE COMPOSÉS FAIBLEMENT SOLUBLES, ET PROCÉDÉS DE FABRICATION ET D'UTILISATION DE FORMULATIONS DE TELS COMPOSÉS
Abstract
(EN) The subject invention relates to novel soluble forms of planar ring structured organic compounds including flavonoids, and their production. The invention also includes the use of these novel formulations of planar ring structured organic compounds in the preparation of formulations and products. The invention also relates to a wide variety of applications of the formulations of the invention. The subject invention includes novel soluble forms and various formulations of flavonoids. Further, the invention includes novel methods of manufacturing the flavonoid formulations. The invention also relates to a wide variety of applications of the flavonoid formulations.
(FR) L'invention concerne de nouvelles formes solubles de composés organiques structurés à noyau plan, y compris des flavonoïdes, et un procédé de production de celles-ci. L'invention comprend aussi l'utilisation de ces nouvelles formulations de composés organiques structurés à noyau plan dans la préparation de formulations et de produits. L'invention concerne aussi un large éventail d'applications des formulations de l'invention. L'invention comprend de nouvelles formes solubles et diverses formulations de flavonoïdes. Elle concerne en outre de nouveaux procédés de fabrication de ces formulations de flavonoïdes. L'invention concerne de plus un large éventail d'applications de ces formulations de flavonoïdes.
Latest bibliographic data on file with the International Bureau