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Machine translation
1. (WO2012053691) PEGYLATED INTERFERON ALPHA ISOMER
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/053691    International Application No.:    PCT/KR2010/008080
Publication Date: 26.04.2012 International Filing Date: 16.11.2010
IPC:
C07K 14/56 (2006.01)
Applicants: SONG, Eun Kyung [KR/KR]; (KR) (For US Only).
KOH, Donghyun [KR/KR]; (KR) (For US Only).
KOH, Choong Hyun [KR/KR]; (KR) (For US Only).
KIM, Yeon Hyang [KR/KR]; (KR) (For US Only).
SONG, Gwan Gyu [KR/KR]; (KR) (For US Only).
KOH, Hyung Kon [KR/KR]; (KR) (For US Only).
R & D BIOLAB LTD [KR/KR]; 3-114 Eunma Apt Daechi-dong, Kangnam-gu Seoul 135-778 (KR) (For All Designated States Except US)
Inventors: SONG, Eun Kyung; (KR).
KOH, Donghyun; (KR).
KOH, Choong Hyun; (KR).
KIM, Yeon Hyang; (KR).
SONG, Gwan Gyu; (KR).
KOH, Hyung Kon; (KR)
Priority Data:
10-2010-0103420 22.10.2010 KR
Title (EN) PEGYLATED INTERFERON ALPHA ISOMER
(FR) ISOMÈRE D'INTERFÉRON ALPHA PÉGYLÉ
(KO) 페길레이션된 인터페론 알파 동종체
Abstract: front page image
(EN)The present invention relates to production of human interferon having an increased persistence of specific activity, through genetic manipulation by transformation of an amino acid sequence in a specific region of human interferon alpha, then binding an appropriate size PEG to the transformed amino acid region.
(FR)Cette invention concerne la production d'interféron humain présentant une persistance d'activité spécifique accrue, induite par une manipulation génétique par transformation d'une séquence d'acides aminés dans une région spécifique de l'interféron alpha humain, puis par liaison d'un PEG de taille appropriée à la région d'acides aminés transformée.
(KO)본 발명은 사람 인터페론 알파의 특정 부위에 아미노산 서열의 변형을 유전자 조작에 의해 실시하고, 아미노산 변형이 이루어진 부위에 적정한 크기의 PEG를 결합시킴으로써 사람 인터페론의 비활성 증대와 지속성을 갖도록 제작함에 있다.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: Korean (KO)
Filing Language: Korean (KO)