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1. (WO2012052679) METHOD FOR PREPARING FIBRILLAR COLLAGEN
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/052679    International Application No.:    PCT/FR2011/052435
Publication Date: 26.04.2012 International Filing Date: 18.10.2011
IPC:
A61L 27/24 (2006.01)
Applicants: UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) [FR/FR]; 4, Place Jussieu F-75005 Paris (FR) (For All Designated States Except US).
DE SA PEIXOTO, Paulo [BR/FR]; (FR) (For US Only).
MOSSER, Gervaise [FR/FR]; (FR) (For US Only)
Inventors: DE SA PEIXOTO, Paulo; (FR).
MOSSER, Gervaise; (FR)
Agent: GROSSET-FOURNIER, Chantal, Catherine; GROSSET-FOURNIER & DEMACHY 54, rue Saint-Lazare F-75009 Paris (FR)
Priority Data:
1058521 19.10.2010 FR
Title (EN) METHOD FOR PREPARING FIBRILLAR COLLAGEN
(FR) PROCEDE DE PREPARATION DE COLLAGENE FIBRILLE
Abstract: front page image
(EN)The invention relates to a method for preparing a matrix of pure fibrillar collagen. Said method includes a step of the fibrillogenesis of type I collagen, optionally combined with type V collagen, optionally in a liquid-crystal phase, said step being carried out in an aqueous medium at a pH of between 3.5 and 12, advantageously between 3.5 and 5.5 without a buffer or cross-linking agent, without using an internal guide matrix to orient the fibrils during the fibrillogenesis, and without applying tension to the ends of the fibrils.
(FR)Procédé de préparation d'une matrice de collagène pur fîbrillé comprenant une étape de fïbrillogenèse d'un collagène de type I, éventuellement associé à un collagène de type V, en phase cristalline liquide ou non, ladite étape étant réalisée dans un milieu aqueux, à un pH compris entre 3,5 et 12, avantageusement compris entre 3,5 et 5,5 en l'absence de tampon et d'agent réticulant, sans l'aide d'une matrice de guidage interne pour orienter les fibrilles lors de la fïbrillogenèse et sans application d'une tension à l'extrémité des fibrilles.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: French (FR)
Filing Language: French (FR)