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1. (WO2012052390) N-2-(2-PYRIDINYL)-4-PYRIMIDINYL-BETA-ALANINE DERIVATIVES AS INHIBITORS OF HISTONE DEMETHYLASE JMJD3
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/052390    International Application No.:    PCT/EP2011/068085
Publication Date: 26.04.2012 International Filing Date: 17.10.2011
IPC:
C07D 403/04 (2006.01), C07D 403/14 (2006.01), C07D 413/14 (2006.01), C07D 417/14 (2006.01), C07D 409/14 (2006.01), A61K 31/506 (2006.01), A61P 35/00 (2006.01), A61P 37/02 (2006.01), A61P 29/00 (2006.01)
Applicants: GLAXO GROUP LIMITED [GB/GB]; 980 Great West Road Brentford Middlesex TW8 9GS (GB) (For All Designated States Except US).
ATKINSON, Stephen John [GB/GB]; (GB) (For US Only).
BARKER, Michael David [GB/GB]; (GB) (For US Only).
CAMPBELL, Matthew [GB/GB]; (GB) (For US Only).
HUMPHREYS, Philip [GB/GB]; (GB) (For US Only).
LIDDLE, John [GB/GB]; (GB) (For US Only).
SHEPPARD, Robert John [GB/GB]; (GB) (For US Only).
WILSON, David [GB/GB]; (GB) (For US Only)
Inventors: ATKINSON, Stephen John; (GB).
BARKER, Michael David; (GB).
CAMPBELL, Matthew; (GB).
HUMPHREYS, Philip; (GB).
LIDDLE, John; (GB).
SHEPPARD, Robert John; (GB).
WILSON, David; (GB)
Agent: LEAROYD, Stephanie Anne; GlaxoSmithKline Global Patents (CN925.1) 980 Great West Road Brentford Middlesex TW8 9GS (GB)
Priority Data:
61/394,563 19.10.2010 US
1112607.5 22.07.2011 GB
Title (EN) N-2-(2-PYRIDINYL)-4-PYRIMIDINYL-BETA-ALANINE DERIVATIVES AS INHIBITORS OF HISTONE DEMETHYLASE JMJD3
(FR) DÉRIVÉS DE N-2-(2-PYRIDINYL)-4-PYRIMIDINYL-BÊTA-ALANINE EN TANT QU'INHIBITEURS D'HISTONE DÉMÉTHYLASE JMJD3
Abstract: front page image
(EN)A method of treating autoimmune diseases or conditions in a mammal, such as a human, which comprises the administration of a therapeutically effective amount of histone demethylase enzymes of formula (I).
(FR)L'invention concerne une méthode de traitement de maladies autoimmunes ou d'états autoimmuns chez un mammifère, tel qu'un être humain, qui comprend l'administration d'une quantité thérapeutiquement efficace d'enzymes histone déméthylase de formule (I).
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)