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1. (WO2012051476) MID-INFRARED IMAGING OF MICROARRAYS
Latest bibliographic data on file with the International Bureau

Pub. No.: WO/2012/051476 International Application No.: PCT/US2011/056248
Publication Date: 19.04.2012 International Filing Date: 14.10.2011
IPC:
C12Q 1/68 (2006.01)
C CHEMISTRY; METALLURGY
12
BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
Q
MEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
1
Measuring or testing processes involving enzymes or micro-organisms; Compositions therefor; Processes of preparing such compositions
68
involving nucleic acids
Applicants:
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES [US/US]; National Institutes of Health Office of Technology Transfer 6011 Executive Boulevard Suite 325, MSC 7660 Bethesda, Maryland 20892-7660, US (AllExceptUS)
MOSSOBA, Magdi M. [US/US]; US (UsOnly)
AL-KHALDI, Sufian [US/US]; US (UsOnly)
SCHOEN, Brianna [US/US]; US (UsOnly)
YAKES, Betsy Jean [US/US]; US (UsOnly)
Inventors:
MOSSOBA, Magdi M.; US
AL-KHALDI, Sufian; US
SCHOEN, Brianna; US
YAKES, Betsy Jean; US
Agent:
LECUYER, Karen A.; CANTOR COLBURN LLP 20 Church Street, 22nd Floor Hartford, Connecticut 06103, US
Priority Data:
61/393,63515.10.2010US
Title (EN) MID-INFRARED IMAGING OF MICROARRAYS
(FR) IMAGERIE DE MICROPUCES DANS LE MOYEN INFRAROUGE
Abstract:
(EN) Described herein are methods for mid-infrared imaging of nucleic acid microarrays by employing mid-infrared reflective labels combined with detection in the reflection mode. The methods described herein provide intrinsic image contrast, and permit detection of DNA microarray hybridization on infrared absorbing substrates such as glass slides.
(FR) La présente invention concerne des procédés d'imagerie de micropuces à acide nucléique dans le moyen infrarouge par l'utilisation de marqueurs réfléchissants dans le moyen infrarouge combinés à une détection dans le mode réflexion. Les procédés décrits dans la présente invention permettent un contraste d'image intrinsèque et permettent la détection d'une hybridation de micropuce à ADN sur des substrats absorbant l'infrarouge, tels que des lames de verre.
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Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW
African Regional Intellectual Property Organization (ARIPO) (BW, GH, GM, KE, LR, LS, MW, MZ, NA, RW, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG)
Publication Language: English (EN)
Filing Language: English (EN)
Also published as:
US20140148352