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1. (WO2012050714) CARTILAGE OLIGOMERIC MATRIX PROTEIN (COMP)-GROWTH FACTOR COMPLEXES AND USES THEREOF
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/050714    International Application No.:    PCT/US2011/051610
Publication Date: 19.04.2012 International Filing Date: 14.09.2011
IPC:
C07K 19/00 (2006.01), C07K 14/47 (2006.01), C07K 14/475 (2006.01), A61L 27/22 (2006.01), A61L 27/58 (2006.01), A61F 2/00 (2006.01), A61K 38/17 (2006.01), A61P 19/00 (2006.01)
Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA [US/US]; 1111 Franklin Street 12th Floor Oakland, California 94607-5200 (US) (For All Designated States Except US).
HAUDENSCHILD, Dominik [US/US]; (US) (For US Only).
DI CESARE, Paul [US/US]; (US) (For US Only).
YIK, Jasper [CN/US]; (US) (For US Only)
Inventors: HAUDENSCHILD, Dominik; (US).
DI CESARE, Paul; (US).
YIK, Jasper; (US)
Agent: BORING, Landin, F.; Kilpatrick Townsend & Stockton LLP Two Embarcadero Center, 8th Floor San Francisco, California 94111-3834 (US)
Priority Data:
61/393,850 15.10.2010 US
Title (EN) CARTILAGE OLIGOMERIC MATRIX PROTEIN (COMP)-GROWTH FACTOR COMPLEXES AND USES THEREOF
(FR) COMPLEXES DE PROTÉINE DE MATRICE OLIGOMÈRE DE CARTILAGE (COMP)-FACTEUR DE CROISSANCE ET LEURS UTILISATIONS
Abstract: front page image
(EN)The present invention relates to protein complexes or scaffold comprising cartilage oligomeric matrix protein (COMP) polypeptides bound to one or more growth factors, and methods of their use in promoting chondrogenesis and/or osteogenesis, and repair of cartilage and bone lesions.
(FR)La présente invention concerne des complexes ou des structures comprenant des polypeptides de protéine de matrice oligomère de cartilage (COMP) liés à un ou plusieurs facteurs de croissance, et des procédés pour les utiliser dans l'activation de la chondrogenèse et/ou de l'ostéogenèse, et la réparation des lésions cartilagineuses et osseuses.
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, QA, RO, RS, RU, RW, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)