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1. (WO2012050591) HYDROGEL FORMULATION FOR DERMAL AND OCULAR DELIVERY
Latest bibliographic data on file with the International Bureau   

Pub. No.:    WO/2012/050591    International Application No.:    PCT/US2010/053566
Publication Date: 19.04.2012 International Filing Date: 21.10.2010
IPC:
A01N 37/18 (2006.01), A61K 31/65 (2006.01)
Applicants: RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY [US/US]; Old Queens Somerset Street New Brunswick, New Jersey 08901 (US) (For All Designated States Except US).
SINKO, Patrick J. [US/US]; (US) (For US Only).
DESHMUKH, Manjeet [IN/US]; (US) (For US Only).
ANUMOLU, SivaNaga S. [IN/US]; (US) (For US Only).
MENJOGE, Anupa R. [IN/IN]; (IN) (For US Only).
GORDON, Marion K. [US/US]; (US) (For US Only)
Inventors: SINKO, Patrick J.; (US).
DESHMUKH, Manjeet; (US).
ANUMOLU, SivaNaga S.; (US).
MENJOGE, Anupa R.; (IN).
GORDON, Marion K.; (US)
Agent: SUMNER, J. Eric; Fox Rothschild LLP 2000 Market Street, 20th Floor Philadelphia, Pennsylvania 19103 (US)
Priority Data:
61/393,653 15.10.2010 US
Title (EN) HYDROGEL FORMULATION FOR DERMAL AND OCULAR DELIVERY
(FR) FORMULATION D'HYDROGEL POUR UNE ADMINISTRATION DERMIQUE ET OCULAIRE
Abstract: front page image
(EN)Formulations of cross-linkable polymers, capable of forming non-toxic and biocompatible hydrogels in situ, containing at least one of doxycycline or minocycline. Methods of using the hydrogels for treating the skin or ocular tissues of mammals exposed to vesicant compounds such as sulfur mustard (SM), nitrogen mustard (NM) or half mustard (2-chloroethyl ethyl sulfide (CEES)) are also disclosed.
(FR)L'invention concerne des formulations de polymères réticulables, capables de former des hydrogels non toxiques et biocompatibles in situ, contenant au moins l'une parmi la doxycycline ou la minocycline. Elle divulgue aussi des procédés d'utilisation des hydrogels dans le traitement des tissus cutanés ou oculaires de mammifères exposés à des composés vésicants tels que le gaz moutarde au soufre (sulfur mustard - SM), le gaz moutarde à l'azote (nitrogen mustard - NM) ou le gaz demi-moutarde au soufre (sulfure de 2-chloroéthyléthyle (CEES)).
Designated States: AE, AG, AL, AM, AO, AT, AU, AZ, BA, BB, BG, BH, BR, BW, BY, BZ, CA, CH, CL, CN, CO, CR, CU, CZ, DE, DK, DM, DO, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, GT, HN, HR, HU, ID, IL, IN, IS, JP, KE, KG, KM, KN, KP, KR, KZ, LA, LC, LK, LR, LS, LT, LU, LY, MA, MD, ME, MG, MK, MN, MW, MX, MY, MZ, NA, NG, NI, NO, NZ, OM, PE, PG, PH, PL, PT, RO, RS, RU, SC, SD, SE, SG, SK, SL, SM, ST, SV, SY, TH, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, ZA, ZM, ZW.
African Regional Intellectual Property Organization (BW, GH, GM, KE, LR, LS, MW, MZ, NA, SD, SL, SZ, TZ, UG, ZM, ZW)
Eurasian Patent Organization (AM, AZ, BY, KG, KZ, MD, RU, TJ, TM)
European Patent Office (AL, AT, BE, BG, CH, CY, CZ, DE, DK, EE, ES, FI, FR, GB, GR, HR, HU, IE, IS, IT, LT, LU, LV, MC, MK, MT, NL, NO, PL, PT, RO, RS, SE, SI, SK, SM, TR)
African Intellectual Property Organization (BF, BJ, CF, CG, CI, CM, GA, GN, GQ, GW, ML, MR, NE, SN, TD, TG).
Publication Language: English (EN)
Filing Language: English (EN)